지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 106 - 114 (9page)
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초록· 키워드
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Objective : UV irradiatiion causes skin-aging involving coarse wrinkles, thickning, dyspigmentation, and roughskin surface. This study was aimed to elucidate the anti-winkle activity of complex diet of Korean red ginseng(RG) and fish oil (FO) on UV-induced Photoaging.
Methods : To investigated photo-protective effects of Korean red ginseng and fish oil on UV-induced damagedskins, SKH hairless female mice were randomly divided into six groups 〔control, UV, UV/RG, UV/FO,UV/RG/FO(low), UV/RG/FO(high)〕and orally administered three times a week respectively. UV radiation wasapplied to the backs of the mice three times a week for 8 weeks. Expressions of matrix metalloproteinase(MMP)-3, MMP-13 and tissue inhibitor matrix metalloproteinase (TIMP)-1 in skin were measured byimmunohistochemical staining.
Results : In this study, UVB-induced epidermal hypertropy was diminished by RG group or FO group orcomplex group of RG and FO. Expression levels of MMP-3 and MMP-13 were reduced and expression level ofTIMP-1 was increased by RG group or FO group or complex group of RG and FO. Especially MMP-3 and MMP-13were markedly reduced by diet of FO and complex diet of RG and FO compared with untreated group.
Conclusions : This results suggest that complex diet of RG and FO have a anti-wrinkle activity on UV-inducedphoto-aging and intrinsic aging.
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등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Bang HO / 1976 / The composition of food consumed by Greenland Eskimos / Acta Med. Scand 69 : 200 ~
Bang HO / 1980 / The composition of the Eskimo food in North western Greenland / Am. J Clin Nutr 33 : 2657 ~
Choi KT / 2008 / Botanical characteristics, pharmacological effects and medical components of Korean Panax ginseng CA Meyer / Acta Pharmacol Sin 29 : 1109 ~
Demina NS / 1996 / Collagenolytic enzymes synthesized by microorganism / Mikrobiologiia 65 : 293 ~ 304
DiNicolantonio JJ / 2013 / Omega-3 polyunsaturated fatty acids for the prevention of cardiovascular disease: do formulation, dosage & comparator matter? / Mo Med 110 (6)
Bang HO / 1980 / The composition of the Eskimo food in North western Greenland / Am. J Clin Nutr 33 : 2657 ~
Choi KT / 2008 / Botanical characteristics, pharmacological effects and medical components of Korean Panax ginseng CA Meyer / Acta Pharmacol Sin 29 : 1109 ~
Demina NS / 1996 / Collagenolytic enzymes synthesized by microorganism / Mikrobiologiia 65 : 293 ~ 304
DiNicolantonio JJ / 2013 / Omega-3 polyunsaturated fatty acids for the prevention of cardiovascular disease: do formulation, dosage & comparator matter? / Mo Med 110 (6)
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