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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 537 - 542 (6page)
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Purpose: Some recent trials suggest that postoperative adjuvant radiotherapy (RT) may be safely omitted after breast-conserving surgery (BCS) for some patients with ductal carcinoma in situ (DCIS). In this study, we reviewed clinical outcomes of patients with DCIS treated with partial mastectomy (PM) without adjuvant RT. Materials and Methods: Medical records of 28 patients (29 breasts) with DCIS who were treated with PM, but without RT, between April 1991 and December 2010 were retrospectively analyzed. Based on established criteria (2.0 cm or less in size and no comedonecrosis), 18 patients were treated without RT after PM. Seven patients (8 breasts) who did not receive RT due to refusal were also included in this study. Three other patients were excluded because data concerning comedonecrosis were not available. Results: For the 25 patients included in this study, the mean age of the 18 patients who met the criteria was 47.9±6.2 years, and 47.6±12.7 years for the 7 patients who did not. The mean sizes of the primary tumors were 0.6±0.4 cm and 0.9±0.3 cm, respectively, in these two groups. Among these 25 patients (26 breasts) treated without RT, we observed no ipsilateral breast tumor recurrence or mortality within a mean follow-up of 84 months. Conclusion: Based on this small number of cases, patients with DCIS, who were selected for tumor size less than 2 cm and absence of comedonecrosis, may be treated successfully with BCS; adjuvant RT may be omitted.
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참고문헌 (21)
참고문헌 신청
EORTC Breast Cancer Cooperative Group; EORTC Radiotherapy Group / 2006 / Breast-conserving treatment with or without radiotherapy in ductal carcinoma- in-situ: ten-year resul
Fisher B / 2001 / Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience
Fisher ER / 1999 / Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) eight-year update of Protocol B-17: intraductal carcinoma / Cancer 86 : 429
Fisher ER / 2007 / Pathologic variables predictive of breast events in patients with ductal carcinoma in situ / Am J Clin Pathol 128 : 86 ~ 91
Gilleard O / 2008 / The significance of the Van Nuys prognostic index in the management of ductal carcinoma in situ / World J Surg Oncol 6 : 61 ~
Fisher B / 2001 / Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience
Fisher ER / 1999 / Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) eight-year update of Protocol B-17: intraductal carcinoma / Cancer 86 : 429
Fisher ER / 2007 / Pathologic variables predictive of breast events in patients with ductal carcinoma in situ / Am J Clin Pathol 128 : 86 ~ 91
Gilleard O / 2008 / The significance of the Van Nuys prognostic index in the management of ductal carcinoma in situ / World J Surg Oncol 6 : 61 ~
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