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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 562 - 568 (7page)
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Purpose: A retrospective study was conducted to review the treatment and outcomes of mainly melanomas in acral location in a single institution in Korea, and to evaluate the prognostic significance of anatomic locations of the tumor. Materials and Methods: A retrospective review was completed on 40 patients between 2001 and 2006 to obtain pertinent demographic data, tumor data, treatment characteristics,and follow-up data. Results: Forty melanoma patients were identified and analyzed. Of these, 18 were male and 22 were female patients and the mean age at the time of diagnosis was 55.9 years. Of the tumors, 65% were located on the hands and feet with acral lentiginous melanoma being the most common histological subtype. Univariate analysis for the overall melanoma survival revealed that the thickness of the tumor and the clinical stage have prognostic significances.
The most significant factor as analyzed by a multivariate analysis was shown to be the advanced clinical stage. Acral melanomas did not show statistically significant differences in the age at diagnosis, thickness of the tumor, stage, ulceration, and survival rates compared to non-acral melanomas. There was also no significant difference in the survival rate between the patients treated by amputation versus wide local excision in acral melanomas. Conclusion: In Korean melanoma patients, thickness and advanced stages are significant factors for poorer prognosis.
However, the location of melanoma did not have a significant prognostic value. In treating the melanomas in acral location, local wide excisions resulted in a similar prognosis compared to amputations.
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참고문헌 (29)
참고문헌 신청
Balch CM / 2001 / The new melanoma staging system / Tumori 87 : S64 ~ 68
Bevilacqua RG / 1990 / Axillary dissection in melanoma. Prognostic variables in nodepositive patients / Ann Surg 212 : 125 ~ 131
Boyle P / 1995 / Epidemiology of malignant melanoma / Br Med Bull 51 : 523 ~ 547
Breslow A / 1975 / Tumor thickness, level of invasion and node dissec-tion in stage I cutaneous melanoma / Ann Surg 182 : 572 ~ 575
Chang AE / 1998 / The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeon
Bevilacqua RG / 1990 / Axillary dissection in melanoma. Prognostic variables in nodepositive patients / Ann Surg 212 : 125 ~ 131
Boyle P / 1995 / Epidemiology of malignant melanoma / Br Med Bull 51 : 523 ~ 547
Breslow A / 1975 / Tumor thickness, level of invasion and node dissec-tion in stage I cutaneous melanoma / Ann Surg 182 : 572 ~ 575
Chang AE / 1998 / The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeon
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