지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 1,542 - 1,555 (14page)
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초록· 키워드
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Purpose: Bowel cleansing is generally regarded as time-consuming and unpleasantamong patients. Patients commonly state that bowel preparation provokes more discomfort than the actual colonoscopic examination. The purpose of this study was to compare two regimens of sodium phosphate (NaP) tablets versus polyethylene glycol (PEG) solution for bowel preparation in healthy Korean adults. Materials and Methods: This was a single center, prospective, open-label, investigator-blinded, randomized, controlled-pilot study. A total of 62 healthy Koreansubjects were randomly assigned to two groups (NaP vs. PEG). Efficacy, safety, and patient-related outcomes, as well as procedural parameters, were evaluated. Results: Although there were no significant differences in total Ottawa bowelquality score, fluid scores and the rate of adequate bowel preparation were significantlybetter in the NaP group than the PEG group. Additionally, the NaP group showed better results regarding patient tolerance, satisfaction, preference, and rate of adverse events than the PEG group. Significant fluctuations in specific serum electrolytes were common and of a greater magnitude in the NaP group than the PEG group. However, these abnormalities were transient and did not result in seriouscomplications and side effects. Conclusion: In this study, NaP tablets were shown to be an effective, well-tolerated, and acceptable regimen for bowel preparation. Also, our study suggests that NaP tablets may be safe and can be used as a bowel cleansing agent in healthy adults undergoing elective colonoscopy. Further multicenter, large scale studies are needed to confirm these findings.
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참고문헌 (23)
참고문헌 신청
Adler A / 2013 / Factors determining the quality of screening colonoscopy: a prospective study on adenoma detection rates, from 12,134 examinations (Berlin colonoscopy proje
Chiu HM / 2006 / The impact of colon preparation timing on colonoscopic detection of colorectal neoplasms--a prospective endoscopist-blinded randomized trial / Am J Gastroen
De Silva AP / 2011 / The prone 12 o’clock position reduces ileal intubation time during colonoscopy compared to the left lateral 6 o’clock (standard) position / BMC Gastro
Froehlich F / 2005 / Impact of colonic cleansing on quality and diagnostic yield of colonoscopy:the European Panel of Appropriateness of Gastrointestinal Endoscopy European
Gavin DR / 2013 / The national colonoscopy audit: a nationwide assessment of the quality and safety of colonoscopy in the UK / Gut 62 : 242 ~ 249
Chiu HM / 2006 / The impact of colon preparation timing on colonoscopic detection of colorectal neoplasms--a prospective endoscopist-blinded randomized trial / Am J Gastroen
De Silva AP / 2011 / The prone 12 o’clock position reduces ileal intubation time during colonoscopy compared to the left lateral 6 o’clock (standard) position / BMC Gastro
Froehlich F / 2005 / Impact of colonic cleansing on quality and diagnostic yield of colonoscopy:the European Panel of Appropriateness of Gastrointestinal Endoscopy European
Gavin DR / 2013 / The national colonoscopy audit: a nationwide assessment of the quality and safety of colonoscopy in the UK / Gut 62 : 242 ~ 249
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