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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 732 - 738 (7page)
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Purpose: A recent study demonstrated that exertional desaturation is a predictor of rapid decline in lung function in patients with chronic obstructive pulmonary disease(COPD); however, the study was limited by its method used to detect exertionaldesaturation. The main purpose of this study was to explore whether exertional desaturation assessed using nadir oxygen saturation (SpO2) during the 6-minute walk test (6MWT) can predict rapid lung function decline in patients with COPD. Materials and Methods: A retrospective analysis was performed on 57 patients with moderate to very severe COPD who underwent the 6MWT. Exertional desaturationwas defined as a nadir SpO2 of <90% during the 6MWT. Rapid decline was defined as an annual rate of decline in forced expiratory volume in 1 second (FEV1) ≥50 mL. Patients were divided into rapid decliner (n=26) and non-rapid decliner (n=31) groups. Results: A statistically significant difference in exertional desaturationwas observed between rapid decliners and non-rapid decliners (17 vs. 8, p=0.003). No differences were found between the groups for age, smoking status, BODE index, and FEV1. Multivariate analysis showed that exertional desaturation was a significant independent predictor of rapid decline in patients with COPD (relativerisk, 6.8; 95% CI, 1.8 to 25.4; p=0.004). Conclusion: This study supports that exertional desaturation is a predictor of rapid lung function decline in male patients with COPD.
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참고문헌 (25)
참고문헌 신청
. Kanner RE / 2001 / Lower respiratory illnesses promote FEV(1) decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from t
/ / From the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD)
/ 1995 / Standardization of Spirometry, 1994 Update. American Thoracic Society / Am J Respir Crit Care Med 152 : 1107 ~ 1136
ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories / 2002 / ATS statement: guidelines for the six-minute walk test / Am J Respir Crit Care M
Anthonisen NR / 1994 / Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study / JAMA
/ / From the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD)
/ 1995 / Standardization of Spirometry, 1994 Update. American Thoracic Society / Am J Respir Crit Care Med 152 : 1107 ~ 1136
ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories / 2002 / ATS statement: guidelines for the six-minute walk test / Am J Respir Crit Care M
Anthonisen NR / 1994 / Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study / JAMA
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