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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 753 - 759 (7page)
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초록· 키워드
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Purpose: To investigate clinical implications of delta neutrophil index (DNI) to discriminate adult onset Still’s disease (AOSD) from sepsis. Materials and Methods:We reviewed the medical records of 13 patients with AOSD and 33 gender and age-matched patients with sepsis. In all subjects, microbial tests were performedto exclude or confirm sepsis. All laboratory data were measured two or three times during the first 3 days and represented by their mean levels. DNI was measured automatically by ADVIA 2120 for the first 3 days. Results: There were no significant differences in white blood cell counts, neutrophil proportion, erythrocytesedimentation rate and C-reactive protein between two groups. AOSD patientshad notably lower DNI than sepsis patients regardless of the presence of bacteremia or not. However, both DNI and ferritin were not significant independentfactors for predicting sepsis in the multivariate logistic regression analysis. Meanwhile, the area under the receiver operating characteristic curve (AUROC) of DNI was slightly higher than that of ferritin. When we set DNI of 2.75% as the cut-off value for predicting sepsis, 11 (84.6%) of AOSD patients had a DNI value below 2.75% and 2 (15.4%) of them had a DNI over 2.75% (relative risk for sepsis176). Conclusion: We suggest that DNI may be a useful marker for differential diagnosis of AOSD from sepsis in the early phase as supplementary to ferritin.
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참고문헌 (21)
참고문헌 신청
Ansari-Lari MA / 2003 / Immature granulocyte measurement using the Sysmex XE-2100. Relationship to infection and sepsis / Am J Clin Pathol 120 : 795 ~ 799
Bagnari V / 2010 / Adult-onset Still’s disease / Rheumatol Int 30 : 855 ~ 862
Cavallazzi R / 2010 / Is the band count useful in the diagnosis of infection? An accuracy study in critically ill patients / J Intensive Care Med 25 : 353 ~ 357
Fautrel B / 2001 / Diagnostic value of ferritin and glycosylated ferritin in adult onset Still’s disease / J Rheumatol 28 : 322 ~ 329
Fautrel B / 2002 / Ferritin levels in adult Still’s disease: any sugar? / Joint Bone Spine 69 : 355 ~ 357
Bagnari V / 2010 / Adult-onset Still’s disease / Rheumatol Int 30 : 855 ~ 862
Cavallazzi R / 2010 / Is the band count useful in the diagnosis of infection? An accuracy study in critically ill patients / J Intensive Care Med 25 : 353 ~ 357
Fautrel B / 2001 / Diagnostic value of ferritin and glycosylated ferritin in adult onset Still’s disease / J Rheumatol 28 : 322 ~ 329
Fautrel B / 2002 / Ferritin levels in adult Still’s disease: any sugar? / Joint Bone Spine 69 : 355 ~ 357
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