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연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제56권 제4호
발행연도
2015.1
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968 - 975 (8page)

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Purpose: We evaluated the clinical characteristics and courses of patients with congenitalcystic adenomatoid malformation (CCAM) complicated by pneumonia. Materials and Methods: We retrospectively reviewed the records of 19 adult patientswith surgically confirmed CCAM between March 2005 and July 2013. Results:Eighteen of nineteen patients presented with acute pneumonia symptoms and signs, and inflammatory markers were elevated. On chest computed tomography, all 18 patients had parenchymal infiltration around cystic lesions, 17 (94%) had an air-fluid level, and 2 (11%) had pleural effusion. After antibiotics treatment for a median of 22 days prior to surgery, all acute pneumonia symptoms and signs disappearedin 17 (94%) patients at a median of 10 days. Improvements and normalizationof inflammatory marker levels, occurred in 17 (94%) and 9 (50%) patients at medians of 8 and 17 days, respectively. Radiological improvement was evident in 11 (61%) patients, at a median of 18 days, of these patients, partial radiological improvementoccurred in 10 (56%) and complete radiological resolution in only 1 (6%). One patient (6%) did not improve in terms of clinical, laboratory, or radiologicalfindings despite antibiotic treatment for 13 days. Consequently, after 17 (94%) elective and 1 (6%) emergency surgeries, all patients improved without developmentof complications. Conclusion: We described the clinical characteristics and courses of patients with CCAM complicated by pneumonia, and showed that surgerymay be performed safely after clinicolaboratory improvement is attained upon antibiotic treatment, even in the absence of complete radiological resolution.

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