지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 928 - 936 (9page)
이용수
초록· 키워드
오류제보하기
Purpose: Recent studies show positive association of early repolarization (ER) with the risk of life-threatening arrhythmias in patients with coronary artery disease(CAD). This study was to investigate the relationships of ER with myocardial scarring and prognosis in patients with CAD. Materials and Methods: Of 570 consecutive CAD patients, patients with and without ER were assigned to ER group (n=139) and no ER group (n=431), respectively. Myocardial scar was evaluatedusing cardiac single-photon emission computed tomography. Results: ER group had previous history of myocardial infarction (33% vs. 15%, p<0.001) and lower left ventricular ejection fraction (57±13% vs. 62±13%, p<0.001) more frequentlythan no-ER group. While 74 (53%) patients in ER group had myocardial scar, only 121 (28%) patients had in no-ER group (p<0.001). During follow up, 9 (7%) and 4 (0.9%) patients had cardiac events in ER and no-ER group, respectively (p=0.001). All patients with cardiac events had ER in inferior leads and horizontal/descending ST-segment. Patients with both ER in inferior leads and horizontal/descendingST variant and scar had an increased adjusted hazard ratio of cardiac events (hazard ratio 16.0; 95% confidence interval: 4.1 to 55.8; p<0.001). Conclusion: ER in inferior leads with a horizontal/descending ST variant was associated with increasedrisk of cardiac events. These findings suggest that ER in patients with CAD may be related to myocardial scar rather than pure ion channel problem.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Amsterdam EA / 1988 / Relation of silent myocardial ischemia to ventricular arrhythmias and sudden death / Am J Cardiol 62 : 24I ~ 27I
Antzelevitch C / 2005 / Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association / Circula
Brugada P / 1992 / Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter
Castle CH / 1965 / Electrocardiographic “peri-infarction block”. A clinical and pathologic correlation / Circulation 31 : 403 ~ 408
Furukawa Y / 2013 / Early repolarization pattern associated with su
Antzelevitch C / 2005 / Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association / Circula
Brugada P / 1992 / Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter
Castle CH / 1965 / Electrocardiographic “peri-infarction block”. A clinical and pathologic correlation / Circulation 31 : 403 ~ 408
Furukawa Y / 2013 / Early repolarization pattern associated with su
이 논문의 저자 정보
최근 본 자료
댓글(0)
0