지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 944 - 952 (9page)
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초록· 키워드
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Purpose: The impacts of different time courses and the degree of neointimal growth on neointimal morphology have not yet been sufficiently investigated. Therefore, we evaluated the morphological features of neointimal tissue after drug-eluting stent (DES) implantation using optical coherence tomography (OCT). Materials and Methods: The morphological features of neointimal tissue in stentedsegments with a maximal percentage of cross-sectional area (CSA) stenosis of neointima were evaluated in 507 DES-treated lesions with >100 μm mean neointimalthickness on follow-up OCT. Neointimal tissue was categorized as homogeneous,heterogeneous, layered, or neoatherosclerotic. Results: In lesions with <50% of neointimal CSA stenosis, homogeneous neointima (68.2%) was predominant,followed by heterogeneous neointima (14.1%) and layered neointima (14.1%). In lesions with ≥50% of neointimal CSA stenosis, layered neointima was most frequently observed (68.3%), followed by neoatherosclerotic neointima (25.2%). In subgroup analysis of lesions with ≥50% of neointimal CSA stenosis, 89.5% of the lesions with a stent age <30 months were layered neointima, while 62.3% of the lesions with a stent age ≥30 months were neoatherosclerotic neointima. Conclusion: This study suggests that the OCT-detected morphology of DES neointimal tissue was different according to the follow-up time course and degree of neointimal hyperplasia.
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참고문헌 (16)
참고문헌 신청
Chieffo A / 2009 / Histopathology of clinical coronary restenosis in drug-eluting versus bare metal stents / Am J Cardiol 104 : 1660 ~ 1667
Farb A / 1999 / Pathology of acute and chronic coronary stenting in humans / Circulation 99 : 44 ~ 52
Gonzalo N / 2009 / Optical coherence tomography patterns of stent restenosis / Am Heart J 158 : 284 ~ 293
Habara M / 2013 / Morphological differences of tissue characteristics between early, late, and very late restenosis lesions after first generation drug-eluting stent implanta
Kang SJ / 2011 / Optical coherence tomographic analysis of in-stent neoatherosclerosis after drug-eluting stent implantation / Circulation 123 : 2954 ~ 2963
Farb A / 1999 / Pathology of acute and chronic coronary stenting in humans / Circulation 99 : 44 ~ 52
Gonzalo N / 2009 / Optical coherence tomography patterns of stent restenosis / Am Heart J 158 : 284 ~ 293
Habara M / 2013 / Morphological differences of tissue characteristics between early, late, and very late restenosis lesions after first generation drug-eluting stent implanta
Kang SJ / 2011 / Optical coherence tomographic analysis of in-stent neoatherosclerosis after drug-eluting stent implantation / Circulation 123 : 2954 ~ 2963
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