지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 994 - 998 (5page)
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Purpose: Clostridium difficile (C. difficile) is an important cause of nosocomial diarrhea. Diagnostic methods for detection of C. difficile infection (CDI) are shifting to molecular techniques, which are faster and more sensitive than conventional methods. Although recent advances in these methods have been made in terms of their cost-benefit, ease of use, and turnaround time, anaerobic culture remains an important method for detection of CDI. Materials and Methods: In efforts to evaluatea novel chromogenic medium for the detection of C. difficile (chromID CD agar), 289 fecal specimens were analyzed using two other culture media of blood agar and cycloserine-cefoxitin-fructose-egg yolk agar while enzyme immunosorbentassay and polymerase chain reaction-based assay were used for toxin detection. Results: ChromID showed the highest detection rate among the three culture media. Both positive rate and sensitivity were higher from chromID than other culturemedia. ChromID was better at detecting toxin producing C. difficile at 24 h and showed the highest detection rate at both 24 h and 48 h. Conclusion: Simultaneous use of toxin assay and anaerobic culture has been considered as the most accurate and sensitive diagnostic approach of CDI. Utilization of a more rapid and sensitive chromogenic medium will aid in the dianogsis of CDI.
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참고문헌 (22)
참고문헌 신청
Alcala L / 2008 / Comparison of three commercial methods for rapid detection of Clostridium difficile toxins A and B from fecal specimens / J Clin Microbiol 46 : 3833 ~ 3835
Blossom DB / 2007 / The challenges posed by reemerging Clostridium difficile infection / Clin Infect Dis 45 : 222 ~ 227
Cho SY / 2012 / Detection of Clostridium difficile as a Routine Diagnosis: Comparison of Real-Time PCR and Enzyme Immunoassay / AMERICAN JOURNAL OF CLINICAL PATHOLOGY 137 (3
Darkoh C / 2011 / Novel one-step method for detection and isolation of active-toxin-producing Clostridium difficile strains directly from stool samples / J Clin Microbiol 49
Doing KM / 2012 / Prospective evaluation of the Meridian IllumigeneTM loop-mediated amplification assay and the Gen Probe ProGastroTM Cd polymerase chain reaction assay for t
Blossom DB / 2007 / The challenges posed by reemerging Clostridium difficile infection / Clin Infect Dis 45 : 222 ~ 227
Cho SY / 2012 / Detection of Clostridium difficile as a Routine Diagnosis: Comparison of Real-Time PCR and Enzyme Immunoassay / AMERICAN JOURNAL OF CLINICAL PATHOLOGY 137 (3
Darkoh C / 2011 / Novel one-step method for detection and isolation of active-toxin-producing Clostridium difficile strains directly from stool samples / J Clin Microbiol 49
Doing KM / 2012 / Prospective evaluation of the Meridian IllumigeneTM loop-mediated amplification assay and the Gen Probe ProGastroTM Cd polymerase chain reaction assay for t
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