지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 759 - 764 (6page)
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초록· 키워드
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Purpose: We aimed to determine the prevalence of anti-cyclic citrullinated peptide (anti-CCP) antibodies in a large group of Korean patients with Behçet’s disease (BD), with and without joint involvement, and to compare these findings with the prevalences of anti-CCP antibodies in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Materials and Methods: We tested 189 patients with BD, 105 with RA, and 36 with SLE for anti-CCP antibodies and IgM rheumatoid factor in serum. We reviewed the medical records of patients with BD to investigate their personal and clinical characteristics as well as their laboratory test results. Results: Anti-CCP antibodies were detected in seven of the 189 BD patients (3.7%), at a mean titer of 30.6±44.4 U/mL, in 86 of the 105 RA patients (81.9%) with a mean titer of 198.8±205.7 U/mL, and in nine of the 36 SLE patients (25%) with a mean titer of 180.4±113.9 U/mL. One of the seven anti-CCP-positive BD patients fulfilled the diagnostic criteria for both BD and RA. Five of the seven anti-CCP-positive BD patients (71.4%) had polyarticular joint involvement,and the other two patients (28.6%) had oligoarticular involvement. Conclusion:We determined the prevalence of anti-CCP antibodies in a large group of Korean BD patients with and without joint involvement. Negative anti-CCP test in patients with BD may help to differentiate BD from RA and SLE, all of which present with similar clinical features.
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참고문헌 (24)
참고문헌 신청
/ 1990 / Criteria for diagnosis of Behcet’s disease. International Study Group for Behcet’s Disease / Lancet 335 : 1078 ~ 1080
Bang D / 2001 / Epidemiologic and clinical survey of Behcet’s disease in Korea: the first multicenter study / J Korean Med Sci 16 : 615 ~ 618
Damian-Abrego GN / 2008 / Anti-c
Dilsen N / 1993 / Risk factors for vital organ involvement in Behcet’s disease, In Behcet’s disease. 1st ed / Elsevier Science Publishers : 165 ~ 169
Generini S / 2009 / Anti-hnRNP and other autoantibodies in systemic sclerosis with joint involvement / Rheumatology 48 : 920 ~ 925
Bang D / 2001 / Epidemiologic and clinical survey of Behcet’s disease in Korea: the first multicenter study / J Korean Med Sci 16 : 615 ~ 618
Damian-Abrego GN / 2008 / Anti-c
Dilsen N / 1993 / Risk factors for vital organ involvement in Behcet’s disease, In Behcet’s disease. 1st ed / Elsevier Science Publishers : 165 ~ 169
Generini S / 2009 / Anti-hnRNP and other autoantibodies in systemic sclerosis with joint involvement / Rheumatology 48 : 920 ~ 925
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