지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 215 - 218 (4page)
이용수
초록· 키워드
오류제보하기
Lichen planus (LP) is a common, pruritic and inflammatory disease of the skin, hair follicles and mucous membranes. Immunologic mechanisms, especially cell-mediated immunity, play a major role in triggering the clinical expression of the disease. P-selectin is an adhesion molecule present within endothelial cells and mediates endothelial-leukocyte interactions. Therefore, it is considered that P-selectin plays an important role in LP. The aim of our study is to research the relation between P-selectin and LP.
Serum P-selectin levels were determined with the enzyme- linked immunosorbent sandwich assay method in sera from 40 LP patients and 40 healthy controls.
The serum levels of P-selectin were statistically significantly higher in the patients than in healthy controls (p<0.05), in female patients (39.32+/-11.34pg/ml) than in male patients (31.93+/-9.83 pg/ml) (p<0.01), and in the patients with eruptive form (40.27±9.32pg/ml) than in those with the localised (32.83±9.93 pg/ml) and hypertrophic (31.72±8.39pg/ml) forms (both p<0.01).
In conclusion, we found a meaningful relation between LP and serum P-selectin levels.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
/ 1973 / Lichenoid tissue reactions. A speculative review of the clinical spectrum of epidermal basal cell damage with special reference to erythema dyschromicum perstans 107
/ 1985 / A platelet alpha granule membrane protein (GMP-140) is expressed on the membrane after activation 101 : 880 ~ 886
/ 1989 / Cloning of GMP- 140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation 56 : 1033 ~
/ 1989 / GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies 84 : 92 ~ 99
/ 1989 / Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein G
/ 1985 / A platelet alpha granule membrane protein (GMP-140) is expressed on the membrane after activation 101 : 880 ~ 886
/ 1989 / Cloning of GMP- 140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation 56 : 1033 ~
/ 1989 / GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies 84 : 92 ~ 99
/ 1989 / Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein G
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