지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 510 - 515 (6page)
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Purpose: There are no reports about bone graft and cell therapy for the osteonecrosis of femoral head (ONFH). We prospectively evaluated the clinical results of auto-iliac cancellous bone grafts combined with implantation of autologous bone marrow cells for ONFH. Materials and Methods: Sixty-one hips in 52 patients with ONFH treated with bone graft and cell therapy were enrolled, and the average follow-up of the patients was 68 (60-88) months. Necrotic lesions were classified according to their size by the Steinberg method and location of necrosis. Results:At the last follow-up, the percentage of excellent or good results was 80% (12/15 hips) in the small lesion group, 65% (17/26 hips) in the medium size group, and 28% (6/20 hips) in the large size group. The procedures were a clinical success in 4 of 5 hips (80%) of stage I, 23 of 35 hips (65.7%) of stage II, 7 of 18 hips (38.9%) of stage III, and 1 of 3 hips (33.3%) of stage IV grade, according to the Association Research Circulation Osseous grading system. Among the 20 cases with large sized necrotic lesions, 17 cases were laterally located and this group showed the worst outcomes, with 13 hips (76.5%) having bad or failed clinical results.
Conclusion: The results of the present study suggested that patients who have a large sized lesion or medium sized laterally located lesion would not be good candidates for the head preserving procedure. However, for medium sized lesions,this procedure generated clinical results comparable to those of other head preserving procedures.
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참고문헌 (24)
참고문헌 신청
Camp JF / 1986 / Core decompression of the femoral head for osteonecrosis / J Bone Joint Surg Am 68 : 1313 ~ 1319
Ficat RP / 1985 / Idiopathic bone necrosis of the femoral head. Early diagnosis and treatment / J Bone Joint Surg Br 67 : 3 ~ 9
Gangji V / 2003 / Abnormalities in the replicative capacity of osteoblastic cells in the proximal femur of patients with osteonecrosis of the femoral head / J Rheumatol 30 :
Gangji V / 2004 / Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study / J Bone Joint Surg Am 86-A : 1153 ~ 1160
Hernigou P / 1997 / Abnormalities in the bone marrow of the iliac crest in patients who have osteonecrosis secondary to corticosteroid therapy or alcohol abuse / J Bone Join
Ficat RP / 1985 / Idiopathic bone necrosis of the femoral head. Early diagnosis and treatment / J Bone Joint Surg Br 67 : 3 ~ 9
Gangji V / 2003 / Abnormalities in the replicative capacity of osteoblastic cells in the proximal femur of patients with osteonecrosis of the femoral head / J Rheumatol 30 :
Gangji V / 2004 / Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study / J Bone Joint Surg Am 86-A : 1153 ~ 1160
Hernigou P / 1997 / Abnormalities in the bone marrow of the iliac crest in patients who have osteonecrosis secondary to corticosteroid therapy or alcohol abuse / J Bone Join
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