지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 389 - 395 (7page)
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Purpose: The purpose of the present study was to evaluate the contributing factors to the lymph node status as well as to define the impact of preoperative concurrent chemoradiotherapy (CCRT) on the number of lymph nodes retrieved in mid-low rectal cancer. Materials and Methods: We retrospectively analyzed 277 patients who underwent curative surgical resection for mid-low rectal cancer between 1998 and 2007. Eighty-two patients received long course preoperative CCRT followed by surgery. Results: A mean of 13.12±9.28 lymph nodes was retrieved.
In a univariate analysis, distance from the anal verge, pT stage, pN stage, lymphovascular invasion, preoperative CCRT had significant influence on the number of lymph nodes retrieved. In a multivariate model, patients in the CCRT group had fewer retrieved lymph nodes than the non-CCRT group (p<0.001). Both univariate and multivariate analyses showed that the ypN0 group had fewer retrieved lymph nodes than the ypN1-2 group (p=0.027) in the CCRT group. Conclusion:Preoperative CCRT was an independent risk factor for failure to harvest an appropriate number of lymph nodes, and node-negative patients who received CCRT had fewer lymph nodes harvested.
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참고문헌 (25)
참고문헌 신청
Baxter NN / 2005 / Impact of preoperative radiation for rectal cancer on subsequent lymph node evaluation: a population-based analysis / Int J Radiat Oncol Biol Phys 61 : 42
Baxter NN / 2009 / Is lymph node count an ideal quality indicator for cancer care? / J Surg Oncol 99 : 265 ~ 268
Caplin S / 1998 / For patients with Dukes’ B (TNM Stage II) colorectal carcinoma, examination of six or fewer lymph nodes is related to poor prognosis / Cancer 83 : 666 ~ 6
Chapet O / 2005 / Preoperative radiotherapy for rectal adenocarcinoma: which are strong prognostic factors? / Int J Radiat Oncol Biol Phys 61 : 1371 ~ 1377
Cianchi F / 2002 / Lymph node recovery from colorectal tumor specimens: recommendation for a minimum number of lymph nodes to be examined / World J Surg 26 : 384 ~ 389
Baxter NN / 2009 / Is lymph node count an ideal quality indicator for cancer care? / J Surg Oncol 99 : 265 ~ 268
Caplin S / 1998 / For patients with Dukes’ B (TNM Stage II) colorectal carcinoma, examination of six or fewer lymph nodes is related to poor prognosis / Cancer 83 : 666 ~ 6
Chapet O / 2005 / Preoperative radiotherapy for rectal adenocarcinoma: which are strong prognostic factors? / Int J Radiat Oncol Biol Phys 61 : 1371 ~ 1377
Cianchi F / 2002 / Lymph node recovery from colorectal tumor specimens: recommendation for a minimum number of lymph nodes to be examined / World J Surg 26 : 384 ~ 389
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