지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 1,266 - 1,272 (7page)
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Purpose: Although there is no clinical evidence of nephrotoxicity with the volatile anesthetics currently used in general anesthesia, a better agent should be needed in terms of preserving postoperative renal function in living kidney donors who have only single remaining kidney. The purpose of the current retrospective, single-center study was to evaluate and compare renal function of living kidney donors after nephrectomy under either sevoflurane or desflurane anesthesia. Materials and Methods: From January 2006 through December 2011, a total of 228 donors undergoing video assisted minilaparotomy surgery nephrectomy for kidney donation were retrospectively enrolled in the current study. The donors were categorized into a sevoflurane group or desflurane group based on the type of volatile anesthetic used. We collected laboratory data from the patients preoperatively, immediately after the operation, on the first postoperative day and on the third postoperative day. We also compared renal function of the kidney donors after donor nephrectomy by comparing creatinine level and estimated glomerular filtration rate (eGFR). Results: The decrease in renal function after surgery in both groups was the most prominent on the first postoperative day. There were no significant differences between the two groups in postoperative changes of creatinine or eGFR. Conclusion: Sevoflurane and desflurane can be used safely as volatile anesthetics in donors undergoing nephrectomy.
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참고문헌 (33)
참고문헌 신청
Frink EJ Jr / 1992 / Clinical comparison of sevoflurane and isoflurane in healthy patients / Anesth Analg 74:241~245
Kharasch ED / 1995 / Human kidney methoxyflurane and sevoflurane metabolism. Intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity / Anesthesiology 82:689~699
Conzen PF / 2002 / Low-flow sevoflurane compared with low-flow isoflurane anesthesia in patients with stable renal insufficiency / Anesthesiology 97:578~584
Bito H / 1997 / Effects of low-flow sevoflurane anesthesia on renal function: comparison with high-flow sevoflurane anesthesia and low-flow isoflurane anesthesia / Anesthesiology 86:1231~1237
Vats HS / 2005 / Early postnephrectomy donor renal function: laparoscopic versus open procedure / Transplantation 79:609~612
Kharasch ED / 1995 / Human kidney methoxyflurane and sevoflurane metabolism. Intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity / Anesthesiology 82:689~699
Conzen PF / 2002 / Low-flow sevoflurane compared with low-flow isoflurane anesthesia in patients with stable renal insufficiency / Anesthesiology 97:578~584
Bito H / 1997 / Effects of low-flow sevoflurane anesthesia on renal function: comparison with high-flow sevoflurane anesthesia and low-flow isoflurane anesthesia / Anesthesiology 86:1231~1237
Vats HS / 2005 / Early postnephrectomy donor renal function: laparoscopic versus open procedure / Transplantation 79:609~612
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