지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 1,293 - 1,296 (4page)
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The therapeutic potential of human multipotent mesenchymal stromal cells, especially human adipose tissue-derived stem cells (hASC), is promising. However, there are concerns about the safety of infusion of hASC in human. Recently, we have experienced pulmonary embolism and infarct among family members who have taken multiple infusions of intravenous autologous hASC therapy. A 41-year-old man presented with chest pain for one month. Chest CT showed multiple pulmonary artery embolism and infarct at right lung. Serum D-dimer was 0.8 μg/mL (normal; 0-0.5 μg/mL). He had received intravenous autologous adipose tissue-derived stem cell therapy for cervical herniated intervertebral disc three times (one, two, and three months prior to the visit). His parents also received the same therapy five times and their chest CT also showed multiple pulmonary embolism. These cases represent artificial pulmonary embolisms and infarct after IV injection of hASC. Follow-up chest CT showed spontaneous resolution of lesions in all three patients.
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참고문헌 (13)
참고문헌 신청
Black LL / 2007 / Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronic osteoarthritis of the coxofemoral joints: a randomized, d
Black LL / 2008 / Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the
Brignier AC / 2010 / Embryonic and adult stem cell therapy / J Allergy Clin Immunol 125 (2) : S336 ~ S344
Cyranoski D / 2010 / Korean deaths spark inquiry / Nature 468 : 485 ~
Erickson GR / 2002 / Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo / Biochem Biophys Res Commun 290 : 763 ~ 769
Black LL / 2008 / Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the
Brignier AC / 2010 / Embryonic and adult stem cell therapy / J Allergy Clin Immunol 125 (2) : S336 ~ S344
Cyranoski D / 2010 / Korean deaths spark inquiry / Nature 468 : 485 ~
Erickson GR / 2002 / Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo / Biochem Biophys Res Commun 290 : 763 ~ 769
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