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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 177 - 182 (6page)
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Purpose: The increasing prevalence and global spread of carbapenem-resistant Acinetobacter baumannii (A. baumannii) has become a serious problem. The aim of this study was to investigate molecular and epidemiological characteristics of carbapenem-resistant A. baumannii isolates collected from Korean non-tertiary hospitals. Materials and Methods: Thirty six non-duplicated carbapenem-resistant A. baumannii isolates were collected from 17 non-tertiary hospitals in Korea between 2004 and 2006. Isolates were typed by multilocus sequence typing and repetitive-sequence-based PCR (rep-PCR). Detection of genes encoding OXA carbapenemase and their relationship with ISAba1 was performed by PCR. Results: Two clones were prevalent among 36 isolates: ST69 (17 isolates, 47.2%) and ST92 (19 isolates, 52.8%). Rep-PCR patterns were diverse and revealed that all isolates were clustered into eight band patterns. The ISAba1-activated blaOXA-23-like and ISAba1-activated blaOXA-51-like genes were prevalent among the carbapenem-resistant A. baumannii isolates. Conclusion: The class D β-lactamase genes of A. baumannii were distributed nationwide in non-tertiary Korean hospitals.
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참고문헌 (16)
참고문헌 신청
Bartual SG / 2005 / Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii / J Clin Microbiol 43 : 4382 ~ 43
Clinical and Laboratory Standards Institute / 2010 / Performance Standards for Antimicrobial Susceptibility Testing: Twentieth Informational Supplement M100-S20 / CLSI
Feil EJ / 2004 / eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data / J Bacteriol 186 : 15
Garnacho-Montero J / 2010 / Multiresistant Acinetobacter baumannii infections: epidemiology and management / Curr Opin Infect Dis 23 : 332 ~ 339
Ko KS / 2007 / High rates of resistance to colistin and polymyxin B in subgroups of Acinetobacter baumannii isolates from Korea / J Antimicrob Chemother 60 : 1163 ~ 1167
Clinical and Laboratory Standards Institute / 2010 / Performance Standards for Antimicrobial Susceptibility Testing: Twentieth Informational Supplement M100-S20 / CLSI
Feil EJ / 2004 / eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data / J Bacteriol 186 : 15
Garnacho-Montero J / 2010 / Multiresistant Acinetobacter baumannii infections: epidemiology and management / Curr Opin Infect Dis 23 : 332 ~ 339
Ko KS / 2007 / High rates of resistance to colistin and polymyxin B in subgroups of Acinetobacter baumannii isolates from Korea / J Antimicrob Chemother 60 : 1163 ~ 1167
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