지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 1,197 - 1,202 (6page)
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Purpose: We investigated the effect of total intravenous anesthesia (TIVA) with propofol on postoperative nausea and vomiting (PONV) after robot-assisted laparoscopic radical prostatectomy (RLRP) in patients at low risk of developing PONV, in comparison to balanced anesthesia with desflurane. Materials and Methods: Sixty two patients were randomly assigned to the Des or TIVA group. Propofol and remifentanil were used for induction of anesthesia in both groups and for maintenance of the anesthesia in the TIVA group. In the Des group, anesthesia was maintained with desflurane and remifentanil. In both groups, postoperative pain was controlled using fentanyl-based intravenous patient controlled analgesia,and ramosetron 0.3 mg was administered at the end of surgery. The incidence of PONV, severity of nausea and pain, and requirements of rescue antiemetics and analgesics were recorded. Results: The incidence of nausea in the post-anesthetic care unit was 22.6% in the Des group and 6.5% in the TIVA (p=0.001) group. The incidence of nausea at postoperative 1-6 hours was 54.8% in the Des group and 16.1% in the TIVA group (p=0.001). At postoperative 6-48 hours, there were no significant differences in the incidence of nausea between groups. Conclusion: In order to prevent PONV after RLRP in the early postoperative period, anesthesia using TIVA with propofol is required regardless of patient-related risk factors.
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참고문헌 (24)
참고문헌 신청
Apfel CC / 1999 / A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers / Anesthesiology 91 : 693 ~
Apfel CC / 2004 / A factorial trial of six interventions for the prevention of postoperative nausea and vomiting / N Engl J Med 350 : 2441 ~ 2451
Appadu BL / 1994 / Does propofol interact with D2 dopamine receptors? / Anesth Analg 79 : 1191 ~ 1192
Barann M / 1993 / Inhibition by anaesthetics of 14C-guanidinium flux through the voltage-gated sodium channel and the cation channel of the 5-HT3 receptor of N1E-115 neurobl
Chen X / 2001 / The effect of timing of dolasetron administration on its efficacy as a prophylactic antiemetic in the ambulatory setting / Anesth Analg 93 : 906 ~ 911
Apfel CC / 2004 / A factorial trial of six interventions for the prevention of postoperative nausea and vomiting / N Engl J Med 350 : 2441 ~ 2451
Appadu BL / 1994 / Does propofol interact with D2 dopamine receptors? / Anesth Analg 79 : 1191 ~ 1192
Barann M / 1993 / Inhibition by anaesthetics of 14C-guanidinium flux through the voltage-gated sodium channel and the cation channel of the 5-HT3 receptor of N1E-115 neurobl
Chen X / 2001 / The effect of timing of dolasetron administration on its efficacy as a prophylactic antiemetic in the ambulatory setting / Anesth Analg 93 : 906 ~ 911
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