지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 1,154 - 1,158 (5page)
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Purpose: To investigate gastric juice nitrate/nitrite concentration according to mucosal surface pH extent (area) of gastric corpus intimately contacting the gastric juice. Materials and Methods: We included ninety-nine patients with dyspepsia. To evaluate gastric mucosal surface pH and its extent, gastric chromosocpy was performed by spraying phenol red dye on the corpus mucosa and estimating the extent of area with color changed. Nitrate/nitrite concentrations and pH of gastric juice were measured by ELISA and pH meter, respectively. Silver staining was done to histologically confirm the presence of Helicobacter pylori. Results: Intragastric nitrate/nitrite concentrations in patients, showing phenol red staining mucosa were higher than those of unstaining mucosa (p=0.001): the more extensive in the area of phenol red staining area of corpus, the higher gastric juice pH found (r=0.692, p<0.001). Furthermore, the intragastric nitrate/nitrite concentrations correlated positively with gastric juice pH (r=0.481, p<0.001). Conclusion: The changes of mucosal surface pH and its extent in gastric corpus might affect either pH or nitrate/nitrite level of gastric juice.
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참고문헌 (20)
참고문헌 신청
Gonzalez CA / 1994 / Nutritional factors and gastric cancer in Spain / Am J Epidemiol 139 : 466 ~ 473
Green LC / 1982 / Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids / Anal Biochem 126 : 131 ~ 138
Iijima K / 2003 / Studies of nitric oxide generation from salivary nitrite in human gastric juice / Scand J Gastroenterol 38 : 246 ~ 252
Jonkers D / 1999 / Differential features of gastric cancer patients, either Helicobacter pylori positive or Helicobacter pylori negative / Ital J Gastroenterol Hepatol 31 :
Kodama K / 2003 / Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk? / Eur J Gast
Green LC / 1982 / Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids / Anal Biochem 126 : 131 ~ 138
Iijima K / 2003 / Studies of nitric oxide generation from salivary nitrite in human gastric juice / Scand J Gastroenterol 38 : 246 ~ 252
Jonkers D / 1999 / Differential features of gastric cancer patients, either Helicobacter pylori positive or Helicobacter pylori negative / Ital J Gastroenterol Hepatol 31 :
Kodama K / 2003 / Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk? / Eur J Gast
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