지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 879 - 891 (13page)
이용수
초록· 키워드
오류제보하기
Pathogenic bacteria have increasingly been resisting to antimicrobial therapy. Recently,resistance problem has been relatively much worsened in Gram-negative bacilli. Acinetobacter spp. are typical nosocomial pathogens causing infections and high mortality, almost exclusively in compromised hospital patients. Acinetobacter spp. are intrinsically less susceptible to antibiotics than Enterobacteriaceae, and have propensity to acquire resistance. A surveillance study in Korea in 2009 showed that resistance rates of Acinetobacter spp. were very high: to fluoroquinolone 67%, to amikacin 48%, to ceftazidime 66% and to imipenem 51%. Carbapenem resistance was mostly due to OXA type carbapenemase production in A. baumannii isolates, whereas it was due to metallo-β-lactamase production in non-baumannii Acinetobacter isolates. Colistin-resistant isolates were rare but started to be isolated in Korea. Currently, the infection caused by multidrug-resistant A. baumannii is among the most difficult ones to treat. Analysis at tertiary care hospital in 2010 showed that among the 1,085 isolates of Acinetobacter spp., 14.9% and 41.8% were resistant to seven, and to all eight antimicrobial agents tested, respectively.
It is known to be difficult to prevent Acinetobacter spp. infection in hospitalized patients, because the organisms are ubiquitous in hospital environment. Efforts to control resistant bacteria in Korea by hospitals, relevant scientific societies and government agencies have only partially been successful. We need concerted multidisciplinary efforts to preserve the efficacy of currently available antimicrobial agents, by following the principles of antimicrobial stewardship.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Bergogne-Berezin E / 1996 / Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features / Clin Microbiol Rev 9 : 148 ~ 165
Bouvet PJ / 1987 / Identification and biotyping of clinical isolates of Acinetobacter / Ann Inst Pasteur Microbiol 138 : 569 ~ 578
Brotz-Oesterhelt H / 2010 / Postgenomic strategies in antibacterial drug discovery / Future Microbiol 5 : 1553 ~ 1579
Dortet L / 2006 / Bacterial identification, clinical significance, and antimicrobial susceptibilities of Acinetobacter ursingii and Acinetobacter schindleri, two frequently
Getchell-White SI / 1989 / The inanimate environment of an intensive care unit as a potential source of nosocomial bacteria: evidence for long survival of Acinetobacter calc
Bouvet PJ / 1987 / Identification and biotyping of clinical isolates of Acinetobacter / Ann Inst Pasteur Microbiol 138 : 569 ~ 578
Brotz-Oesterhelt H / 2010 / Postgenomic strategies in antibacterial drug discovery / Future Microbiol 5 : 1553 ~ 1579
Dortet L / 2006 / Bacterial identification, clinical significance, and antimicrobial susceptibilities of Acinetobacter ursingii and Acinetobacter schindleri, two frequently
Getchell-White SI / 1989 / The inanimate environment of an intensive care unit as a potential source of nosocomial bacteria: evidence for long survival of Acinetobacter calc
이 논문의 저자 정보
최근 본 자료
댓글(0)
0