지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 1,016 - 1,021 (6page)
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Purpose: We investigated what kinds of neurotransmitters are related with electroacupuncture (EA) analgesia in an arthritic pain model of rats. Materials and Methods: One hundred rats were assigned to six groups: control, EA, opioid, adrenergic,serotonin and dopamine group. A standardized model of inflammatory arthritis was produced by injecting 2% carrageenan into the knee joint cavity. EA was applied to an acupoint for 30 min in all groups except fo the control group. In the opioid, adrenergic, serotonin and dopamine groups, each receptor antagonist was injected intraperitoneally to their respective group before initiating EA. Results: In the opioid receptor antagonist group, adrenergic receptor antagonist group, serotonin receptor antagonist group, dopamine receptor antagonist group and the control group weight-bearing force decreased significantly from 30 min to 180 min after EA in comparison with the EA group. Conclusion: The analgesic effects of EA are related to opioid, adrenergic, serotonin and dopamine receptors in an arthritic pain model of rats.
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참고문헌 (22)
참고문헌 신청
Baek YH / 2005 / Analgesic effect of electroacupuncture on inflammatory pain in the rat model of collagen-induced arthritis: mediation by cholinergic and serotonergic recept
Ezzo J / 2000 / Is acupuncture effective for the treatment of chronic pain? A systematic review / Pain 86 : 217 ~ 225
Han JS / 1982 / Neurochemical basis of acupuncture analgesia / Annu Rev Pharmacol Toxicol 22 : 193 ~ 220
Han JS / 1984 / Acupuncture mechanisms in rabbits studied with microinjection of antibodies against beta-endorphin, enkephalin and substance P / Neuropharmacology 23 : 1 ~ 5
Huang C / 2004 / Attenuation of mechanical but not thermal hyperalgesia by electroacupuncture with the involvement of opioids in rat model of chronic inflammatory pain / Brai
Ezzo J / 2000 / Is acupuncture effective for the treatment of chronic pain? A systematic review / Pain 86 : 217 ~ 225
Han JS / 1982 / Neurochemical basis of acupuncture analgesia / Annu Rev Pharmacol Toxicol 22 : 193 ~ 220
Han JS / 1984 / Acupuncture mechanisms in rabbits studied with microinjection of antibodies against beta-endorphin, enkephalin and substance P / Neuropharmacology 23 : 1 ~ 5
Huang C / 2004 / Attenuation of mechanical but not thermal hyperalgesia by electroacupuncture with the involvement of opioids in rat model of chronic inflammatory pain / Brai
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