지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 1,025 - 1,027 (3page)
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Long QT syndrome is associated with lethal tachyarrhythmia that can lead to syncope,seizure, and sudden death. Congenital long QT syndrome is a genetic disorder,characterized by delayed cardiac repolarization and prolongation of the QT interval on the electrocardiogram (ECG). Type 2 congenital long QT is linked to mutations in the human ether a go-go-related gene (HERG). There are environmental triggers of adverse cardiac events such as emotional and acoustic stimuli, but fever can also be a potential trigger of life-threatening arrhythmias in long QT syndrome type 2 patients. Herein, we report a healthy young man who experienced fever-induced polymorphic ventricular tachycardia and QT interval prolongation.
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참고문헌 (14)
참고문헌 신청
Amin AS / 2008 / Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome / J Clin Invest 118 : 2552 ~ 2561
Burashnikov A / 2008 / Fever accentuates transmural dispersion of repolarization and facilitates development of early afterdepolarizations and torsade de pointes under long-Q
Guo J / 2005 / Exaggerated block of hERG (KCNH2) and prolongation of action potential duration by erythromycin at temperatures between 37 degrees C and 42 degrees C / Heart R
Kaufman ES / 2009 / Mechanisms and clinical management of inherited channelopathies: long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardi
MacRae CA / 2009 / Closer look at genetic testing in long-QT syndrome: will DNA diagnostics ever be enough / Circulation 120 : 1745 ~ 1748
Burashnikov A / 2008 / Fever accentuates transmural dispersion of repolarization and facilitates development of early afterdepolarizations and torsade de pointes under long-Q
Guo J / 2005 / Exaggerated block of hERG (KCNH2) and prolongation of action potential duration by erythromycin at temperatures between 37 degrees C and 42 degrees C / Heart R
Kaufman ES / 2009 / Mechanisms and clinical management of inherited channelopathies: long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardi
MacRae CA / 2009 / Closer look at genetic testing in long-QT syndrome: will DNA diagnostics ever be enough / Circulation 120 : 1745 ~ 1748
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