지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 476 - 481 (6page)
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초록· 키워드
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Purpose: Although microalbuminuria is known as a predictor of clinical nephropathy and cardiomyopathy, few studies have investigated the incidence and reference range of microalbuminuria in healthy children. This study aimed to establish a reference range and to study the age-related trend for spot urine microalbumin/creatinine ratio in a Korean pediatric population. Materials and Methods: 352 healthy children were studied from July 2007 through March 2010. Height, weight, serum creatinine, spot urine microalbumin/creatinine ratio, and glomerular filtration rate (GFR) were obtained for each subject. We divided the study population into 5 groups according to age, and compared the spot urine microalbumin/creatinine ratio with other variables using one-way analysis of variance (ANOVA), regression analysis and Pearson’s correlation analysis. Results: In this study, the data showed that the spot urine microalbumin/creatinine ratio decreased with age: 1-12 months, 22.72±13.80 mg/mmol (2SD: 3.33-54.40 mg/mmol); 13-28 months, 16.34±9.58 mg/mmol (2SD: 3.16-35.19 mg/mmol); 29-48 months, 13.12±9.74 mg/mmol (2SD: 3.01-41.57 mg/mmol); 4-6 years, 10.58±8.13 mg/mmol (2SD: 0.00-30.19 mg/mmol); and 7-19 years, 5.13±5.44 mg/mmol (2SD: 0.45-14.45 mg/mmol). The spot urine microalbumin/creatinine ratio showed correlation with age, height, height z-score, weight, weight z-score, GFR, body mass index (BMI) and body surface area (BSA). Conclusion: The spot urine microalbumin/creatinine ratio in normal Korean children decreased with age. This ratio could potentially be used to establish reference ranges and cutoff values for Korean children and to predict nephropathy and cardiomyopathy.
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등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Basic J / 2008 / Microalbuminuria in children with vesicoureteral reflux / Ren Fail 30 : 639 ~ 643
Bennett PH / 1995 / Screening and management of microalbuminuria in patients with diabetes mellitus: recommendations to the Scientific Advisory Board of the National Kidney F
Brenner BM / 1992 / The interrelationships among filtration surface area, blood pressure, and chronic renal disease / J Cardiovasc Pharmacol 19 (Suppl 6) : S1 ~ S7
Burgert TS / 2006 / Microalbuminuria in pediatric obesity: Prevalence and relation to other cardiovascular risk factor / Int J Obes (Lond) 30 : 273 ~ 280
Chugh A / 2007 / Microalbuminuria: what is it? Why is it important? What should be done about it? An update / J Clin Hypertens (Greenwich) 9 : 196 ~ 200
Bennett PH / 1995 / Screening and management of microalbuminuria in patients with diabetes mellitus: recommendations to the Scientific Advisory Board of the National Kidney F
Brenner BM / 1992 / The interrelationships among filtration surface area, blood pressure, and chronic renal disease / J Cardiovasc Pharmacol 19 (Suppl 6) : S1 ~ S7
Burgert TS / 2006 / Microalbuminuria in pediatric obesity: Prevalence and relation to other cardiovascular risk factor / Int J Obes (Lond) 30 : 273 ~ 280
Chugh A / 2007 / Microalbuminuria: what is it? Why is it important? What should be done about it? An update / J Clin Hypertens (Greenwich) 9 : 196 ~ 200
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