지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 435 - 444 (10page)
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초록· 키워드
오류제보하기
Cortisol awakening response (CAR) and nighttime cortisol levels have been used as indices of adrenocortical activity. However, population-based statistical information regarding these indices has not been provided in healthy subjects. This study was carried out to provide basic statistical information regarding these indices. Materials and Methods: Cortisol levels were measured in saliva samples collected immediately upon awakening (0 min), 30 min after awakening and in the nighttime on two consecutive days in 133 healthy subjects. Results: We determined the mean [standard deviation (SD)], median (interquartile range) and 5th-95th percentile range for each measure and auxiliary indices for CAR, i.e., the secreted cortisol concentration within 30 min of awakening (CARscc) and absolute and relative increases in cortisol level within 30 min of awakening (CARi and CARi%, respectively). We also determined these values for auxiliary indices derived from nighttime cortisol level, i.e., the ratio of cortisol level 30 min after awakening (CA_30 min) to nighttime level (CA_30 min/NC), as well as absolute and relative decreases in cortisol levels from CA_30 min to nighttime (DCd and DCd%, respectively). We found no significant differences in cortisol level for any time point or in auxiliary indices between collection days, genders and ages. Conclusion: The provided descriptive information and statistics on the CAR and nighttime cortisol level will be helpful to medical specialists and researchers involved in hypothalamus-pituitary-adrenal axis assessment.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Buchanan TW / 2004 / Circadian regulation of cortisol after hippocampal damage in humans / Biol Psychiatry 56 : 651 ~ 656
Chida Y / 2009 / Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis / Biol Psychol 80 : 265 ~ 278
Clow A / 2004 / Hucklebridge F. The awakening cortisol response: methodological issues and significance / Stress 7 : 29 ~ 37
Edwards S / 2001 / Association between time of awakening and diurnal cortisol secretory activity / Psychoneuroendocrinology 26 : 613 ~ 622
Federenko I / 2004 / Free cortisol awakening responses are influenced by awakening time / Psychoneuroendocrinology 29 : 174 ~ 184
Chida Y / 2009 / Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis / Biol Psychol 80 : 265 ~ 278
Clow A / 2004 / Hucklebridge F. The awakening cortisol response: methodological issues and significance / Stress 7 : 29 ~ 37
Edwards S / 2001 / Association between time of awakening and diurnal cortisol secretory activity / Psychoneuroendocrinology 26 : 613 ~ 622
Federenko I / 2004 / Free cortisol awakening responses are influenced by awakening time / Psychoneuroendocrinology 29 : 174 ~ 184
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