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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 1,159 - 1,164 (6page)
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Purpose: Despite new treatment strategies, anemia remains the most prevalent complication in patients with end-stage renal disease (ESRD). We investigated whether 25-hydroxyvitamin D [25(OH)D3] deficiency was associated with anemia in ESRD patients.
Materials and Methods: We reviewed the medical records of 410 ESRD patients who had undergone renal transplantation (RTx) at Yonsei University Health System and who had 25(OH)D3 levels measured at the time of RTx. Patients were divided into two groups based on baseline 25(OH)D3 concentrations: group 1, 25(OH)D3 levels <10 ng/mL; and group 2, 25(OH)D3 levels ≥10 ng/mL.
Results: Using multivariate regression models, 25(OH)D3, age, and erythrocyte-stimulating agent (ESA) dose were found to be significantly associated with hemoglobin (Hb) levels [25(OH)D3: β=0.263, p<0.001; age: β=0.122, p=0.010; ESA dose: β=-0.069, p=0.005]. In addition, logistic regression analysis revealed that patients in group 1 had a significantly higher risk for developing anemia (Hb level <10 g/dL) compared to group 2 patients, even after adjusting for potential risk factors for anemia (odds ratio=3.857; confidence interval=1.091–13.632; p=0.036).
Conclusion: 25(OH)D3 deficiency was significantly associated with anemia in patients with ESRD. Randomized controlled trials are needed to determine whether vitamin D supplementation can improve anemia in these patients.
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등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Astor BC / 2002 / Association of kidney function with anemia: the Third National Health and Nutrition Examination Survey (1988-1994) / Arch Intern Med 162:1401~1408
Golbahar J / 2013 / Association of vitamin D deficiency and hyperparathyroidism with anemia: a crosssectional study / J Blood Med 4:123~128
Wittwer I / 2013 / Iron deficiency anaemia in chronic kidney disease / J Ren Care 39:182~188
Wojcicki JM / 2013 / Hyperphosphatemia is associated with anemia in adults without chronic kidney disease: results from the National Health and Nutrition Examination Survey (NHANES): 2005-2010 / BMC Nephrol 14:178
Shimizu Y / 2014 / Arima K, et al. Association between alkaline phosphatase and anemia in rural Japanese men: The Nagasaki Islands study / Acta Medica Nagasakiensia 58:125~130
Golbahar J / 2013 / Association of vitamin D deficiency and hyperparathyroidism with anemia: a crosssectional study / J Blood Med 4:123~128
Wittwer I / 2013 / Iron deficiency anaemia in chronic kidney disease / J Ren Care 39:182~188
Wojcicki JM / 2013 / Hyperphosphatemia is associated with anemia in adults without chronic kidney disease: results from the National Health and Nutrition Examination Survey (NHANES): 2005-2010 / BMC Nephrol 14:178
Shimizu Y / 2014 / Arima K, et al. Association between alkaline phosphatase and anemia in rural Japanese men: The Nagasaki Islands study / Acta Medica Nagasakiensia 58:125~130
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