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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 1,348 - 1,353 (6page)
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Purpose: Severe hyperkalemia leads to significant morbidity and mortality if it is not immediately recognized and treated. The concentration of potassium (K+) in the serum increases along with deteriorating renal function. The use of point-of-care K+ (POC-K+) in chronic kidney disease (CKD) could reduce the time for an accurate diagnosis and treatment, saving lives. We hypothesized that POC-K+ would accuratelyreport K+ serum level without significant differences compared to reference testing, regardless of the renal function of the patient. Materials and Methods: The retrospective study was performed between January 2008 and September 2011 at an urban hospital in Seoul. The screening program using POC was conducted as a critical pathway for rapid evaluation and treatment of hyperkalemia since 2008. When a patient with CKD had at least one warning symptom or sign of hyperkalemia,both POC-K+ and routine laboratory tests were simultaneously ordered. The reliability of the two assays for serum-creatinine was assessed by intra-class correlationcoefficient (ICC) analysis using absolute agreement of two-way mixed model. Results: High levels of reliability were found between POC and the laboratory reference tests for K+ (ICC=0.913, 95% CI 0.903--0.922) and between two tests for K+ according to changes in the serum-creatinine levels in CKD patients. Conclusion:The results of POC-K+ correlate well with values obtained from reference laboratorytests and coincide with changes in serum-creatinine of patients with CKD.
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참고문헌 (13)
참고문헌 신청
/ / Desirable Specifications for Total Error, Imprecision, and Bias, derived from intra- and inter-individual biologic variation
An JN / 2012 / Severe hyperkalemia requiring hospitalization: predictors of mortality / CRITICAL CARE 16 (6)
Bloom BM / 2013 / A comparison of measurements of sodium, potassium, haemoglobin and creatinine between an Emergency Department-based point-of-care machine and the hospital
Chhapola V / 2013 / A comparative study on reliability of point of care sodium and potassium estimation in a pediatric intensive care unit / Indian J Pediatr 80 : 731 ~ 735
Hsieh MF / 2011 / Higher serum potassium level associated with late stage chronic kidney disease / Chang Gung Med J 34 : 418 ~ 425
An JN / 2012 / Severe hyperkalemia requiring hospitalization: predictors of mortality / CRITICAL CARE 16 (6)
Bloom BM / 2013 / A comparison of measurements of sodium, potassium, haemoglobin and creatinine between an Emergency Department-based point-of-care machine and the hospital
Chhapola V / 2013 / A comparative study on reliability of point of care sodium and potassium estimation in a pediatric intensive care unit / Indian J Pediatr 80 : 731 ~ 735
Hsieh MF / 2011 / Higher serum potassium level associated with late stage chronic kidney disease / Chang Gung Med J 34 : 418 ~ 425
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