지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 392 - 395 (4page)
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초록· 키워드
오류제보하기
The Human Leukocyte Antigen (HLA) typing of large groups of patients with various autoimmune diseases has demonstrated that some HLA alleles occur at higher frequencies in specific diseases than in the general population. Chronic urticaria has been shown to have an autoimmune basis by a previous study which found an association between chronic urticaria and specific HLA groups. We investigated the HLA subtypes of Turkish chronic urticaria patients. For this purpose 42 Turkish patients with chronic urticaria and 115 healthy controls were typed for HLA-DR and DQ by PCR-SSP (Polymerase Chain Reaction Sequence Specific Primers) low resolution DNA technique. We found an increased frequency of DR4 (42.9%, p=0.01) in chronic urticaria patients in comparison with that in healthy controls. This study supports the hypothesis that HLA alleles may be involved in the pathogenesis of chronic urticaria and that they appear to be directly involved in the initiation of the immune response.
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등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
/ 1978 / HLA antigens and urticaria 261 : 213 ~ 215
/ 1978 / Lack of linkage between hereditary angioedema and the A and B loci of the HLA System 35 : 132 ~ 136
/ 1982 / Hereditary angioneurotic edema and HLA types in two Danish families 273 : 347 ~ 348
/ 1985 / HLA and lymphocyte histamine sensitivity in mastocytosis 77 : 430 ~ 432
/ 1987 / Familial exercise-induced anaphylaxis 58 : 257 ~ 259
/ 1978 / Lack of linkage between hereditary angioedema and the A and B loci of the HLA System 35 : 132 ~ 136
/ 1982 / Hereditary angioneurotic edema and HLA types in two Danish families 273 : 347 ~ 348
/ 1985 / HLA and lymphocyte histamine sensitivity in mastocytosis 77 : 430 ~ 432
/ 1987 / Familial exercise-induced anaphylaxis 58 : 257 ~ 259
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