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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 66 - 75 (10page)
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Purpose: We aimed to externally validate the prediction model we developed for having bladder outlet obstruction (BOO) and requiring prostatic surgery using 2 independent data sets from tertiary referral centers, and also aimed to validate a mobile app for using this model through usability testing.
Methods: Formulas and nomograms predicting whether a subject has BOO and needs prostatic surgery were validated with an external validation cohort from Seoul National University Bundang Hospital and Seoul Metropolitan Government-Seoul National University Boramae Medical Center between January 2004 and April 2015. A smartphone-based app was developed, and 8 young urologists were enrolled for usability testing to identify any human factor issues of the app.
Results: A total of 642 patients were included in the external validation cohort. No significant differences were found in the baseline characteristics of major parameters between the original (n=1,179) and the external validation cohort, except for the maximal flow rate. Predictions of requiring prostatic surgery in the validation cohort showed a sensitivity of 80.6%, a specificity of 73.2%, a positive predictive value of 49.7%, and a negative predictive value of 92.0%, and area under receiver operating curve of 0.84. The calibration plot indicated that the predictions have good correspondence. The decision curve showed also a high net benefit. Similar evaluation results using the external validation cohort were seen in the predictions of having BOO. Overall results of the usability test demonstrated that the app was user-friendly with no major human factor issues.
Conclusions: External validation of these newly developed a prediction model demonstrated a moderate level of discrimination, adequate calibration, and high net benefit gains for predicting both having BOO and requiring prostatic surgery. Also a smartphone app implementing the prediction model was user-friendly with no major human factor issue.
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참고문헌 (16)
참고문헌 신청
Abrams P / 2002 / The standardisation of terminology of lower urinary tract function : report from the Standardisation Sub-committee of the International Continence Society /
Chia SJ / 2003 / Correlation of intravesical prostatic protrusion with bladder outlet obstruction / BJU Int 91 : 371 ~ 374
Cruz Zapata B / 2014 / Mobile PHRs compliance with Android and iOS usability guidelines / J Med Syst 38 : 81 ~
Debray TP / 2015 / A new framework to enhance the interpretation of external validation studies of clinical prediction models / J Clin Epidemiol 68 : 279 ~ 289
Kaplan SA / 1995 / Transition zone index as a method of assessing benign prostatic hyperplasia: correlation with symptoms, urine flow and detrusor pressure / J Urol 154 : 17
Chia SJ / 2003 / Correlation of intravesical prostatic protrusion with bladder outlet obstruction / BJU Int 91 : 371 ~ 374
Cruz Zapata B / 2014 / Mobile PHRs compliance with Android and iOS usability guidelines / J Med Syst 38 : 81 ~
Debray TP / 2015 / A new framework to enhance the interpretation of external validation studies of clinical prediction models / J Clin Epidemiol 68 : 279 ~ 289
Kaplan SA / 1995 / Transition zone index as a method of assessing benign prostatic hyperplasia: correlation with symptoms, urine flow and detrusor pressure / J Urol 154 : 17
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