지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 261 - 266 (6page)
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초록· 키워드
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Purpose: To analyze the baseline clinical factors and medication treatment strategy used in cases with medication treatment failure of benign prostatic hyperplasia (BPH).
Methods: From January 2006 to December 2009, 677 BPH patients with at least 3 months of treatment with medication were enrolled. We analyzed clinical factors by medication failure (n=161) versus maintenance (n=516), by prostate size (less than 30 g, n=231; 30 to 50 g, n=244; greater than 50 g, n=202), and by prostate-specific antigen (PSA) levels (less than 1.4 ng/mL, n=324; more than 1.4 ng/mL, n=353).
Results: Age, combination medication rate, PSA, and prostate volume were statistically different between the medication treatment failure and maintenance groups. By prostate size, the PSA and medication failure rates were relatively higher and the medication period was shorter in patients with a prostate size of more than 30 g. The combination medication rate was higher in patients with a prostate size of more than 50 g. The medication failure rate and prostate volume were higher in patients with a PSA level of more than 1.4 ng/mL. However, the combination treatment rate was not significantly different in patients with a PSA level lower than 1.4 ng/mL. Suggestive cutoffs for combination medication are a prostate volume of 34 g and PSA level of 1.9 ng/mL.
Conclusions: The clinical factors associated with medication failure were age, treatment type, and prostate volume. Combination therapy should be considered more in Korea in patients with a PSA level higher than 1.4 ng/mL and a prostate volume of between 30 and 50 g to prevent medication failure.
목차
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참고문헌 (14)
참고문헌 신청
Anderson JB / 2001 / The progression of benign prostatic hyperplasia: examining the evidence and determining the risk / Eur Urol 39 : 390 ~ 399
Emberton M / 2008 / Benign prostatic hyperplasia as a progressive disease: a guide to the risk factors and options for medical management / Int J Clin Pract 62 : 1076 ~ 1086
Emberton M / 2008 / Understanding patient and physician perceptions of benign prostatic hyperplasia in Europe:The Prostate Research on Behaviour and Education (PROBE) Survey
Hong SJ / 2003 / Identification of baseline clinical factors which predict medical treatment failure of benign prostatic hyperplasia: an observational cohort study / Eur Urol
Jacobsen SJ / 1997 / Natural history of prostatism: risk factors for acute urinary retention / J Urol 158 : 481 ~ 487
Emberton M / 2008 / Benign prostatic hyperplasia as a progressive disease: a guide to the risk factors and options for medical management / Int J Clin Pract 62 : 1076 ~ 1086
Emberton M / 2008 / Understanding patient and physician perceptions of benign prostatic hyperplasia in Europe:The Prostate Research on Behaviour and Education (PROBE) Survey
Hong SJ / 2003 / Identification of baseline clinical factors which predict medical treatment failure of benign prostatic hyperplasia: an observational cohort study / Eur Urol
Jacobsen SJ / 1997 / Natural history of prostatism: risk factors for acute urinary retention / J Urol 158 : 481 ~ 487
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