Puropose: The purpose of this study was to evaluate the relationship between lower urinary
tract symptoms (LUTS) and the metabolic syndrome in the elderly male.
Material and methods: The metabolic syndrome group of 348 patients (64.4±8.6 years old) and
the control group of 150 patients (66.0±7.0 years old) were included in the study. The voiding
factors, such as International Prostate Symptom Score (IPSS), quality of life score, prostate volume,
maximal urine flow rate, residual urine volume, and prostate-specific antigen (PSA) were investigated.
Waist circumference, blood pressure, fasting glucose, HDL-cholesterol, triglyceride were measured
for the evaluation of the metabolic syndrome.
Results: Waist circumference (β=0.025, p<0.001), systolic (β=0.004, p<0.05) and diastolic blood
pressure (β=0.006, p<0.05) were positively correlated with prostate volume. In the logistic regression
analysis of voiding factors according to metabolic syndrome factors, the patients who have
central obesity (Odds ratio [OR]=2.931), central obesity and hypertension (OR=3.598), central obesity
and diabetes (OR=2.508), hypertension and low HDL-cholesterolemia (OR=2.326), central obesity,
hypertension and diabetes (OR=3.083), central obesity, hypertension and low HDL cholesterolemia
(OR=3.440) represented a significantly increased age-adjusted risk of benign prostatic enlargement
(25g or more). OR of symptomatic benign prostatic hyperplasia (BPH) was 3.178 in the patients
with cental obesity, and 2.381 in the patients with both central obesity and hypertension.
Conclusions: In male elderly, the metabolic syndrome was closely related with LUTS and its
main risk factor was central obesity, represented as waist circumference. (J Korean Continence Soc
2008;12:27-35)
Puropose: The purpose of this study was to evaluate the relationship between lower urinary
tract symptoms (LUTS) and the metabolic syndrome in the elderly male.
Material and methods: The metabolic syndrome group of 348 patients (64.4±8.6 years old) and
the control group of 150 patients (66.0±7.0 years old) were included in the study. The voiding
factors, such as International Prostate Symptom Score (IPSS), quality of life score, prostate volume,
maximal urine flow rate, residual urine volume, and prostate-specific antigen (PSA) were investigated.
Waist circumference, blood pressure, fasting glucose, HDL-cholesterol, triglyceride were measured
for the evaluation of the metabolic syndrome.
Results: Waist circumference (β=0.025, p<0.001), systolic (β=0.004, p<0.05) and diastolic blood
pressure (β=0.006, p<0.05) were positively correlated with prostate volume. In the logistic regression
analysis of voiding factors according to metabolic syndrome factors, the patients who have
central obesity (Odds ratio [OR]=2.931), central obesity and hypertension (OR=3.598), central obesity
and diabetes (OR=2.508), hypertension and low HDL-cholesterolemia (OR=2.326), central obesity,
hypertension and diabetes (OR=3.083), central obesity, hypertension and low HDL cholesterolemia
(OR=3.440) represented a significantly increased age-adjusted risk of benign prostatic enlargement
(25g or more). OR of symptomatic benign prostatic hyperplasia (BPH) was 3.178 in the patients
with cental obesity, and 2.381 in the patients with both central obesity and hypertension.
Conclusions: In male elderly, the metabolic syndrome was closely related with LUTS and its
main risk factor was central obesity, represented as waist circumference. (J Korean Continence Soc
2008;12:27-35)