지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 143 - 150 (8page)
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초록· 키워드
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Purpose: To evaluate the effect of age on the efficacy and safety of holmium laser enucleation of the prostate (HoLEP) for the treatment of symptomatic benign prostatic hyperplasia (BPH).
Methods: A total of 579 patients underwent HoLEP procedure performed by a single surgeon (SJO) between December 2009 and May 2013. The perioperative and functional outcomes of patients in the age groups of 50–59 (group A, n=44), 60–69 (group B, n=253), 70–79 (group C, n=244), and ≥80 years (group D, n=38) were compared. The Clavien-Dindo system was used to evaluate clinical outcomes. The International Prostate Symptom Score (IPSS), maximum urinary flow rate (Qmax), postvoid residual (PVR) urine volume, and urinary continence were used to assess functional outcomes.
Results: In this study, the patients ≥80 years had significantly higher presence of hypertension (P=0.007), total prostate volumes (P=0.024), transitional zone volume (P=0.002), American Society of Anesthesiologists scores (P=0.006), urinary retention (P=0.032), and anticoagulation use (P=0.008) at preoperative period. Moreover, the mean values of operation time, enucleation time, morcellation time, and enucleation weight were higher in group D compared with other group patients (P=0.002, P=0.010, P<0.01, and P=0.009, respectively). Patients aged ≥80 years had a longer hospital stay time (2.9±1.8 days) than other groups (group A, 2.3±0.7 days; group B, 2.3±0.7 days vs. group C, 2.4±0.7 days; P=0.001). All groups were similar in regard to the incidence of complications (Clavien-Dindo grade) post operatively (P>0.05). All the patients in the present study showed improvement in functional outcomes after HoLEP. By the sixth month, there were no significant differences in IPSS, quality of life, Qmax, and PVR among the groups (P>0.05).
Conclusions: Compared with younger patients, the patients aged ≥80 years had a similar overall morbidity and 6-month functional outcomes of HoLEP. HoLEP is a safe and effective treatment for BPH among the elderly.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
El-Husseiny T / 2011 / Transurethral ethanol ablation of the prostate for symptomatic benign prostatic hyperplasia: long-term follow-up / J Endourol 25:477~480
Lepor H / 2012 / Djavan B. α-Blockers for benign prostatic hyperplasia:the new era / Curr Opin Urol 22:7~15
Holman CD / 1999 / Mortality and prostate cancer risk in 19,598 men after surgery for benign prostatic hyperplasia / BJU Int 84:37~42
Michalak J / 2015 / HoLEP: the gold standard for the surgical management of BPH in the 21(st) Century / Am J Clin Exp Urol 3:36~42
Jeong CW / 2012 / Enucleation ratio efficacy might be a better predictor to assess learning curve of holmium laser enucleation of the prostate / Int Braz J Urol 38:362~371
Lepor H / 2012 / Djavan B. α-Blockers for benign prostatic hyperplasia:the new era / Curr Opin Urol 22:7~15
Holman CD / 1999 / Mortality and prostate cancer risk in 19,598 men after surgery for benign prostatic hyperplasia / BJU Int 84:37~42
Michalak J / 2015 / HoLEP: the gold standard for the surgical management of BPH in the 21(st) Century / Am J Clin Exp Urol 3:36~42
Jeong CW / 2012 / Enucleation ratio efficacy might be a better predictor to assess learning curve of holmium laser enucleation of the prostate / Int Braz J Urol 38:362~371
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