지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 37 - 47 (11page)
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초록· 키워드
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Transient receptor potential vanilloid type-1 channel (TRPV1) is a non-selective cation channel with a preference for calcium ions that is able to sense a vast range of endogenous physical and chemical stimuli and plays an important role in transducing the sensations of noxious heat and pain signaling. Recent studies showed that TRPV1 is widely expressed in different tissues and organs beyond the sensory nerves and has multiple biological effects that are involved in functional regulation in the pancreas, blood vessel, adipose tissue and liver. To further understand the link between TRPV1 and cardiometabolic diseases, we reviewed the role of TRPV1 in hypertension, diabetes, obesity, and dyslipidemia. This review provides new insights into the involvement of TRPV1 channels in the pathogenesis of cardiometabolic disorders and implicates this channel as a potential therapeutic target for the management of cardiometabolic diseases.
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등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Ahuja KD / 2006 / Effects of chili consumption on postprandial glucose, insulin, and energy metabolism / American Journal of Clinical Nutrition 84 : 63 ~ 69
American Heart Association Nutrition Committee / 2006 / Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition
Bibbins-Domingo K / 2010 / Projected effect of dietary salt reductions on future cardiovascular disease / The New England Journal of Medicine 362 : 590 ~ 599
Brunzell JD / 2008 / Lipoprotein management in patients with cardiometabolic risk: consensus statement from the American Diabetes Association and the American College of Card
Caterina MJ / 1997 / The capsaicin receptor: a heat-activated ion channel in the pain pathway / Nature 389 : 816 ~ 824
American Heart Association Nutrition Committee / 2006 / Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition
Bibbins-Domingo K / 2010 / Projected effect of dietary salt reductions on future cardiovascular disease / The New England Journal of Medicine 362 : 590 ~ 599
Brunzell JD / 2008 / Lipoprotein management in patients with cardiometabolic risk: consensus statement from the American Diabetes Association and the American College of Card
Caterina MJ / 1997 / The capsaicin receptor: a heat-activated ion channel in the pain pathway / Nature 389 : 816 ~ 824
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