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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 57 - 62 (6page)
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초록· 키워드
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Purpose: We used technetium-99m dimercaptosuccinic acid (DMSA) scintigraphy to identify factors predictive of renal cortical defects in infants <3 months of age with urinary tract infections (UTIs).
Methods: We retrospectively reviewed data on infants <3 months of age with culture-proven UTIs treated at a single center from March 2010 to February 2016.
Blood samples were obtained for laboratory evaluation prior to commencement of antibiotic therapy. The therapeutic delay time (TDT) and therapeutic response time (TRT) were recorded. All patients were divided into two groups depending on features of their DMSA scans. We compared the demographic, clinical, and la boratory characteristics of the two groups.
Results: A total of 119 infants (94 males and 25 females; mean age, 56.9±21.3 days) were included. Cortical defects were evident in the DMSA scans of 47 cases (39.5%). In infants with such defects, the peak temperatures (38.9±0.57℃ vs.
38.4±0.81℃, P=0.001), the absolute neutrophil counts (8,920±4,460/mm vs.
7,290±4,090/mm, P=0.043), and the C-reactive protein (CRP) levels (6.49±4.33 mg/dL vs. 3.21±2.81 mg/dL, P=0.001) were significantly higher than those in infants without cortical defects. The TDT was also longer in those with cortical defects (P=0.037).
Conclusion: We found that a TDT ≥8.5 hr (odds ratio [OR] 5.81), a peak temperature ≥38.3℃ (OR 6.19), and a CRP level ≥4.96 mg/dL (OR 7.26) predicted abnormal DMSA scan results in infants <3 months of age with UTIs.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Hoberman A / 1993 / Prevalence of urinary tract infection in febrile infants / J Pediatr 123:17~23
Bachur RG / 2001 / Predictive model for serious bacterial infections among infants younger than 3 months of age / Pediatrics 108:311~316
Jakobsson B / 1992 / 99mTechnetium-dimercaptosuccinic acid scan in the diagnosis of acute pyelonephritis in children : relation to clinical and radio logical findings / Pediatr Nephrol 6:328~334
Jacobson SH / 1992 / Long-term prognosis of post-infectious renal scarring in relation to radiological findings in childhood-a 27-year follow-up / Pediatr Nephrol 6:19~24
Winberg J / 1982 / Clinical pyelonephritis and focal renal scarring. A selected review of pathogenesis, prevention, and prognosis / Pediatr Clin North Am 29:801~814
Bachur RG / 2001 / Predictive model for serious bacterial infections among infants younger than 3 months of age / Pediatrics 108:311~316
Jakobsson B / 1992 / 99mTechnetium-dimercaptosuccinic acid scan in the diagnosis of acute pyelonephritis in children : relation to clinical and radio logical findings / Pediatr Nephrol 6:328~334
Jacobson SH / 1992 / Long-term prognosis of post-infectious renal scarring in relation to radiological findings in childhood-a 27-year follow-up / Pediatr Nephrol 6:19~24
Winberg J / 1982 / Clinical pyelonephritis and focal renal scarring. A selected review of pathogenesis, prevention, and prognosis / Pediatr Clin North Am 29:801~814
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