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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 69 - 73 (5page)
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Purpose: The aim of this study was to compare the clinical and laboratory features of infants with roseola infantum due to human herpesvirus 6 (HHV6) infection and those with urinary tract infection (UTI).
Methods: We retrospectively reviewed the medical records of children who were hospitalized at Cheil General Hospital and Women’s Health Care Center, College of Medicine, Dankook University, and diagnosed as having HHV6 infection or UTI.
Results: Among the infants admitted between September 2014 and May 2016, 92 (male, 45 and female, 47) were included in the study and divided into a HHV6 infection group (n=50) and a UTI group (n=42). The relative risk of UTI compared with that of HHV6 infection increased with pyuria (P<0.001), increased with leuko cytosis (mean white blood cell [WBC] count, 15,048±5,756/mm 3 vs 87,916±54,056/ mm 3 ; P<0.001), increased with C-reactive protein (CRP) level (4.89±4.85 mg/dL vs 1.04±1.76 mg/dL; P<0.001), and younger age (6.3±3.2 months vs 18.3±12.6 months; P<0.001). The relative risk of HHV6 infection compared with that of UTI increased with fever duration (4.3±1.7 days vs 2.8±1.7 days; P<0.001) and de creased with platelet (PLT) count (373±94×10 3 /mm 3 vs 229±90×10 3 /mm 3 ; P< 0.001). No significant differences were found between the HHV6 groups according to the presence or absence of pyuria.
Conclusion: Pyuria, age, fever duration, WBC count, CRP level, and PLT count were the differentiating factors of HHV6 infection from UTI. However, sterile pyuria can occur in children with HHV6 infection. In the presence of pyuria, CRP level and PLT count were the strong predictors of UTI compared with HHV6.
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참고문헌 (15)
참고문헌 신청
Hall CB / 1990 / Herpes and the rash of roses : a new virus, HHV-6, as a cause of an old childhood disease, roseola / Pediatric annals 19:517~521
Cherry JD / 2014 / Feigin and Cherry’s Textbook of Pediatric Infectious Diseases / Elsevier Saunders
Asano Y / 1991 / Severity of human herpesvirus-6 viremia and clinical findings in infants with exanthem subitum / The Journal of pediatrics 118:891~895
Zerr DM / 2005 / A population-based study of primary human herpesvirus 6 infection / The New England journal of medicine 352:768~776
Asano Y / 1994 / Clinical features of infants with primary human herpesvirus 6 infection(exanthem subitum, roseola infantum) / Pediatrics 93:104~108
Cherry JD / 2014 / Feigin and Cherry’s Textbook of Pediatric Infectious Diseases / Elsevier Saunders
Asano Y / 1991 / Severity of human herpesvirus-6 viremia and clinical findings in infants with exanthem subitum / The Journal of pediatrics 118:891~895
Zerr DM / 2005 / A population-based study of primary human herpesvirus 6 infection / The New England journal of medicine 352:768~776
Asano Y / 1994 / Clinical features of infants with primary human herpesvirus 6 infection(exanthem subitum, roseola infantum) / Pediatrics 93:104~108
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