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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 37 - 43 (7page)
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초록· 키워드
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This study was conducted to investigate the prevalence and genotypes of extended-spectrum β-lactamase (ESBL) in 377 Escherichia coli isolated from healthy and sick animals. Two isolates (0.5%), each of which were isolated from diseased swine and chicken, respectively, were confirmed as ESBL producing isolates by double disk synergy test, and showed a multidrug resistant phenotype. Minimum inhibitory concentration of cefotaxime for the two ESBL producing isolates were 3∼4 times higher than those of ceftazidime, respectively. By PCR and sequencing, one isolate from swine have both bla_CTX-15 and bla_TEM-1, and one isolate from chicken have bla_CTX-15 and bla_TEM-116. Also, these genes were transferred to E. coli J53 by conjugation. These two isolates showed unrelated pulsed-field gel electrophoresis. To our knowledge, this is the first time that bla_TEM-116 gene was identified in E. coli isolated from animals in Korea. These results suggest more prudent use of third- generation cephalosporins, and surveillance and monitoring for ESBL producing E. coli in both animals and their environments should be necessary.
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참고문헌 (22)
참고문헌 신청
Ambler RP / 1991 / A standard numbering scheme for the class A beta-lactamases / Biochem J 273 : 269 ~ 270
Bauernfeind A / 1990 / A new plasmidic cefotaximase in a clinical isolate of Escherichia coli / Infection 18 (5) : 294 ~ 298
Bonnet R / 2004 / Growing group of extended-spectrum b-lactamases: The CTX-M- enzymes / Antimicrob Agents Chemother 48 (1) : 1 ~ 14
Bradford PA / 2001 / Extended-spectrum b-lactamases in the 21st century: Characterization, epidemiology, and detection of this important resistance threat / Clin Microbiol Re
Bradley DE / 1980 / Specification of surface mating systems among conjugative drug resistance plasmids in Escherichia coli K-12 / J Bacteriol 143 (3) : 1466 ~ 1470
Bauernfeind A / 1990 / A new plasmidic cefotaximase in a clinical isolate of Escherichia coli / Infection 18 (5) : 294 ~ 298
Bonnet R / 2004 / Growing group of extended-spectrum b-lactamases: The CTX-M- enzymes / Antimicrob Agents Chemother 48 (1) : 1 ~ 14
Bradford PA / 2001 / Extended-spectrum b-lactamases in the 21st century: Characterization, epidemiology, and detection of this important resistance threat / Clin Microbiol Re
Bradley DE / 1980 / Specification of surface mating systems among conjugative drug resistance plasmids in Escherichia coli K-12 / J Bacteriol 143 (3) : 1466 ~ 1470
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