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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 194 - 202 (9page)
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초록· 키워드
오류제보하기
Agaricus brasiliensis, belonging to the family Agaricaceae of Agaricales, Basidiomycota, has been used for edible and medicinal purposes. This study was initiated to evaluate the antioxidant, anti-diabetic, and nitric oxide inhibitory activities of fruiting bodies of A. brasiliensis extracted with methanol. The HPLC analysis of phenolic compounds from the mushroom extracts identified 10 phenolic compounds including gallic acid, procatechuic acid, chlorogenic acid, (−)-epicatechin, vanillin, rutin hydrate, naringin, quercetin, formononetin, and biochanin-A. The free radical scavenging activities of methanol extract were lower than that of positive control, BHT. The chelating effects of methanol extract were significantly higher than those of the positive control, BHT at the all concentrations tested. The methanol extract exhibited the lower reducing power activities compared with the positive control at the 0.5∼6.0 mg/mL concentration. The mushroom extract inhibited the -glucosidase activity by 54.48% and 78.43% at the 1.0 and 2.0 mg/mL while acarbose, the positive control, inhibited the -glucosidase activity by 51.77% and 81.81% at the same concentrations, respectively. Nitric oxide (NO) production in lipopolysaccahride (LPS) induced RAW 264.7 cells were inhibited by the methanol extracts in a concentration dependent manner. Therefore, it is concluded that fruiting bodies of A. brasiliensis contained natural antioxidant, anti-diabetic, and anti-inflammatory substances which can be useful for human health.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Alam N / 2011 / Phenolic compounds concentration and appraisal of antioxidant and antioxidant and antityrosinase activities from the fruiting bodies of Pleurotus eryngii / Ad
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181 : 1199 ~ 1200
Carvajal AE / 2012 / Bioactives of fruiting bodies and submerged culture mycelia of Agaricus brasiliensis (A. blazei) and their antioxidant properties / LWT-Food Sci Technol
Gulcin I / 2003 / Antioxidant and analgesic activities of turpentine of Pinus nigra Arn. subsp. pallsiana (Lamb.) Holmboe / J. Ethnopharmacol 86 : 51 ~ 58
Kim MY / 2008 / Phenolic compound concentration and antioxidant activities of edible and medicinal mushrooms from Korea / J Agric Food Chem 56 : 7265 ~ 7270
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181 : 1199 ~ 1200
Carvajal AE / 2012 / Bioactives of fruiting bodies and submerged culture mycelia of Agaricus brasiliensis (A. blazei) and their antioxidant properties / LWT-Food Sci Technol
Gulcin I / 2003 / Antioxidant and analgesic activities of turpentine of Pinus nigra Arn. subsp. pallsiana (Lamb.) Holmboe / J. Ethnopharmacol 86 : 51 ~ 58
Kim MY / 2008 / Phenolic compound concentration and antioxidant activities of edible and medicinal mushrooms from Korea / J Agric Food Chem 56 : 7265 ~ 7270
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