지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 79 - 84 (6page)
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초록· 키워드
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Children and adolescents normally have higher Alkaline phosphatase levels than adults. This study was conducted to provide basic data about pediatric reference intervals for ALP. The data from the 2011 Korean National Health and Nutrition Examination Survey was used. Analysis was done for 847 Children and Adolescents (443 boys and 404 girls) aged 10 to 19. The method of p -NPP & EAE buffer was used to get the data. The highest ALP levels were found in boys aged 12 to 13, the reference interval being 653∼1,518 IU/L; the levels decreased for those over 13 years old. In the case of girls, the highest ALP levels were found with those aged between 11 and 12, the reference interval being 463∼1,598 IU/L; the levels decreased after 12 years of age. The mean difference in all age groups was statistically significant, except for those aged 10 to 11 and 11 to 12. Therefore, it is suggested that pediatric reference intervals should be divided into three groups according to gender. Complementing data about children and adolescents below 10 years old were not included in this study and will be much needed in the next trial.
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참고문헌 (29)
참고문헌 신청
Shinowara G / 1942 / Estimation of serum inorganic phosphate and “acid” and “alkaline” phosphatase activity / J Biol Chem 142:921~933
Tietz NW / 1983 / A reference method for measurement of alkaline phosphatase activity in human serum / Clin Chem 29:751~761
Togari A / 1987 / Highly sensitive assay for alkaline and acid phosphatase activity by high-performance liquid chromatography with electrochemical detection / J Chromatogr 417:41~46
Turan S / 2011 / Serum alkaline phosphatase levels in healthy children and evaluation of alkaline phosphatase z-scores in different types of rickets / J Clin Res Pediatr Endocrinol 3:7~11
/ / Korean Association of Quality Assurance
Tietz NW / 1983 / A reference method for measurement of alkaline phosphatase activity in human serum / Clin Chem 29:751~761
Togari A / 1987 / Highly sensitive assay for alkaline and acid phosphatase activity by high-performance liquid chromatography with electrochemical detection / J Chromatogr 417:41~46
Turan S / 2011 / Serum alkaline phosphatase levels in healthy children and evaluation of alkaline phosphatase z-scores in different types of rickets / J Clin Res Pediatr Endocrinol 3:7~11
/ / Korean Association of Quality Assurance
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