지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 273 - 278 (6page)
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초록· 키워드
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Sertoli cell tumor(SCT) of the testicle arises from the supporting cells within the seminiferous tubules. SCT is common in dogs, especially in cryptorchid testicles, but also has been reported in the stallion, ram, cat, and bull. Sertoli cell tumor sample was collected from 7-years male german shepherd. In this study, SCT arose from one testicle. Sample size is approximately 1.7 cm in diameter and it has a round form. In the microscopic, cells within the tumor variably resemble Sertoli cells(SCs) that normally populate the seminiferous tubules and interstitial area. There is abundant stroma of dense, mature fibrous connective tissue in SCT. In the immunohistochemical staining, cytokeratin AE1/AE3 was not expressed in the control and SCT. S-100 protein was expressed by SCs, germ cells and fibrous connective tissue of SCT. Melan A was expressed by leydig cells(LCs) of SCT. A study by using S-100 and melan A in canine SCT was almost never carried out. S-100 and melans A is considered to suggest for diagnosis and pathogenesis of canine SCTs. Inhibin-alpha and Vimentin were well known as the marekers of SCTs. Also, they were expressed by Sertoli cells and LSs of SCT in this study.
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참고문헌 (23)
참고문헌 신청
Angela LD / 2006 / Extratesticular interstitial and Sertoli cell tumors in previously neutered dogs and cats: A report of 17 cases / Can Vet J 47 : 763 ~ 766
Arumugam T / 2010 / S100P: a novel therapeutic target for cancer / Amino Acids : 1 ~ 7
Banco B / 2010 / An Immunohistochemical study of normal and neoplastic canine Sertoli cells / J Comp Path 143 : 239 ~ 247
Braun S / 2000 / Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer / N Engl J Med 342 : 525 ~ 533
Busam KJ / 1998 / Immunoreactivity for A103, an antibody to melan-A (Mart-1), in adrenocortical and other steroid tumors / Am J Surg Pathol 22 : 57 ~ 63
Arumugam T / 2010 / S100P: a novel therapeutic target for cancer / Amino Acids : 1 ~ 7
Banco B / 2010 / An Immunohistochemical study of normal and neoplastic canine Sertoli cells / J Comp Path 143 : 239 ~ 247
Braun S / 2000 / Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer / N Engl J Med 342 : 525 ~ 533
Busam KJ / 1998 / Immunoreactivity for A103, an antibody to melan-A (Mart-1), in adrenocortical and other steroid tumors / Am J Surg Pathol 22 : 57 ~ 63
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