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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국동물위생학회(구 한국가축위생학회) 한국가축위생학회지 한국가축위생학회지 제32권 제3호
발행연도
2009.1
수록면
189 - 200 (12page)

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The purpose of this study was to evaluate the effect of a subsequent infection of PCV2 on piglets with PEDV. In clinical signs, the signs observed in dual infected with PEDV and PCV2 piglets and alone infected with PEDV piglets ranged from diarrhoea to vomiting and dehydration. Dual infected piglets developed signs of anorexia, vomiting and watery diarrhoea within 12 hpi. Nevertheless alone infected piglets caused pasty diarrhea at first. In mortality, dual infections showed 25%, but alone infections showed 8.3%, respectively. In gross findings, piglets of dual infections group appeared the severe findings of congestion, distension of lumen, contaning curdes of undigested milk in stomach milder than those of alone infections group. In histopathological findings, piglets of dual infection group appeared the more severe findings of villous atrophy and fusion, congesion, exfoliation, vacuolation, squamation, loss of cilia and proliferation of crypt. Significant (P⁄0.05) decrease in VH : CD ratio in dual infected piglets compared to piglets from alone PEDV infections. In immunohistochemical findings, strong hybridization signals in dual infections were seen in areas of moderate to severe villous atrophy or vacuolation with positive cells arranged continuously over the villi. In the lumen, exfoliated enterocytes were strongly positive in dual infected piglets. The number of PEDV-positive cells in dual infected pigs was significantly higher than that in alone PEDV-infected piglets.

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