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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 35 - 43 (9page)
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Salmonellosis has caused heavy losses in swine industry and implications for public health. Recently, the urgent problem of antibiotic resistance due to multidrug-resistant Salmonella spp. has been on the rise. The use of host-specific bateriophages as a biocontrol is one possible alternative. In this study, clinical signs, growth performance, quantification and detection of antigen, histopathological changes of gastrointestinal tracts were analyzed comparatively in weaned piglets according to administration of bac-teriophages and challenge with Salmonella (S.) Typhimurium. Piglets challenged with S. Typhimurium after administered with bacteriophages showed reduced clinical signs, higher growth performance, lower bacterial shedding, lower quantificational value of antigens in intestines, higher V/C ratio and higher the number of goblet cells in intestines than piglets administered without bacteriophage and challenged with S. Typhimurium. These results indicate that feeding contained with bacteriophages has effect to prevent infection of S. Typhimurium in weaned piglets and suggest that a use of bacteriophage can be considered a valid antibiotic alternative.
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참고문헌 (39)
참고문헌 신청
Khakhria R / 1991 / Distribution of Salmonella enteritidis phage types in canada / Epidemiol Infect 106:25~32
Su Hwa Lee / 2009 / A multiplex real-time PCR for differential detection and quantification of Salmonella spp., Salmonella enterica serovar Typhimurium and Enteritidis in meats / Journal of Veterinary Science 10(1):43~51
Letellier A / 2001 / Host response to various treatments to reduce Salmonella infections in swine / Can J Vet Res 65:168~172
Li BT / 2001 / Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide / Can J Anim Sci 81:511~516
Loc Carrillo C / 2005 / Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens / Appl Environ Microbiol 71:6554~6563
Su Hwa Lee / 2009 / A multiplex real-time PCR for differential detection and quantification of Salmonella spp., Salmonella enterica serovar Typhimurium and Enteritidis in meats / Journal of Veterinary Science 10(1):43~51
Letellier A / 2001 / Host response to various treatments to reduce Salmonella infections in swine / Can J Vet Res 65:168~172
Li BT / 2001 / Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide / Can J Anim Sci 81:511~516
Loc Carrillo C / 2005 / Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens / Appl Environ Microbiol 71:6554~6563
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