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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 103 - 109 (7page)
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초록· 키워드
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Asia1/Shamir that has been recommended by World Reference Laboratory for foot-and-mouth disease (FMD) is used as a vaccine strain, and is being prepared in many countries including Korea. Although it is assumed that vaccine strain Asia1/Shamir has a wide antigenicity, sufficient molecular biological analysis has not been accomplished yet. Complete genome sequence analysis showed that the region with the most severe variations was 1D region of structural protein-coding sequence; particularly amino acid 141∼157 residues in 1D region RGD sites for binding to susceptible cells. In addition, five amino acids in 1D region were identified as characteristic sites that are different from other known Asia1 viruses. Asia1/Shamir strain was shown to be genetically similar to group VI that had occurred in the Middle East, but showed low level of genetic similarity to the group V viruses that had occurred in the Southeast Asia and China. It is considered that, if these viruses, group I and II including group V are introduced into Korea, care would be paid in case of inoculating the vaccine strain Shamir available in Korea.
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참고문헌 (14)
참고문헌 신청
Bachrach HL / 1968 / Foot-and-mouth disease / Annu Rev Microbiol 22 : 201 ~ 244
Biswas S / 2006 / Sequence analysis of the non-structural 3A and 3C protein-coding regions of foot-and-mouth disease virus serotype Asia1 field isolates from an endemic count
Grubman MJ / 1985 / Capsid intermediates assembled in a foot-and-mouth disease virus genome RNA-programmed cell-free translation system and in infected cells / J Virol 56 (1)
Hammond J / 2009 / OIE/FAO World Reference Laboratory report, April-June 2009, Foot-and-mouth Disease : 1 ~ 29
Hammond J / 2009 / OIE/FAO World Reference Laboratory report, January-March 2009, Foot-and-mouth Diasease : 1 ~ 33
Biswas S / 2006 / Sequence analysis of the non-structural 3A and 3C protein-coding regions of foot-and-mouth disease virus serotype Asia1 field isolates from an endemic count
Grubman MJ / 1985 / Capsid intermediates assembled in a foot-and-mouth disease virus genome RNA-programmed cell-free translation system and in infected cells / J Virol 56 (1)
Hammond J / 2009 / OIE/FAO World Reference Laboratory report, April-June 2009, Foot-and-mouth Disease : 1 ~ 29
Hammond J / 2009 / OIE/FAO World Reference Laboratory report, January-March 2009, Foot-and-mouth Diasease : 1 ~ 33
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