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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 118 - 123 (6page)
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Antimicrobial agents have been used in poultry for treatment of bacterial infections or additives over the past half century. However, increasing antimicrobial resistance has led to selective pressure for therapeutic use in humans and made treatment of bacterial infection more difficult. In this study, we examined the prevalence of plasmid mediated antimicrobial resistant determinants for resistance to -lactam, quinolone, and aminoglycoside in Enterobacteriaceae isolates obtained from chickens in Gyeongsang provinces, and correlation between the resistant genes and antimicrobial resistance rate was also assessed. A total of 43 Enterobacteriaceae isolates were recovered from 40 chickens at Gyeongsang provinces in Korea. Antimicrobial susceptibility was determined by disk diffusion method. PCR and DNA sequencing were performed to characterize the antimicrobial resistant genes. Of the 43 Enterobacteriaceae isolates tested, 2 isolates harbored blaCTX-M-14 gene, and 2 and 5 strains contained qnrS and aac(6 ’)-Ib-cr genes, respectively. A total of 43 isolates displayed a relatively lower susceptible rate ranging between 0.0 and 23.3% to most of the antimicrobial agents, except cefepime, ceftazidime, and cefaclor. We confirmed that plasmid mediated antimicrobial resistant determinants were distributed in Enterobacteriaceae isolates from chickens. Investigation of the genes and monitoring of antimicrobial resistance rate is required to prevent further spreading of antimicrobial resistant genes among Enterobacteriaceae isolates.
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참고문헌 (19)
참고문헌 신청
Lee K / 2002 / blaVIM-2cassette-containing novel integrons in metallo--lactamase-producing Pseudomonas aeruginosa and Pseudomonas putida isolates disseminated in a Korean hospital / Antimicrob Agents Chemother 46:1053~1058
Lee K / 2005 / Novel acquired metallo--lactamase gene, bla(SIM-1), in a class 1integron from Acinetobacter baumannii clinical isolates from Korea / Antimicrob Agents Chemother 49:4485~4491
권영일 / 2007 / 국내 축산 환경 중의 항생제 내성균 모니터링에 관한 연구 / 한국미생물·생명공학회지 35(1):17~25
Rubin JE / 2014 / Extended-spectrum -lactamase, carbapenemase and AmpC producing Enterobacteriaceae in companion animals / Vet Microbiol 170:10~18
김명희 / 2010 / Molecular Characteristics of Extended Spectrum β-Lactamases in Escherichia coli and Klebsiella pneumoniae and the Prevalence of qnr in Extended Spectrum β-Lactamase Isolates in a Tertiary Care Hospital in Korea / Yonsei Medical Journal 51(5):768~774
Lee K / 2005 / Novel acquired metallo--lactamase gene, bla(SIM-1), in a class 1integron from Acinetobacter baumannii clinical isolates from Korea / Antimicrob Agents Chemother 49:4485~4491
권영일 / 2007 / 국내 축산 환경 중의 항생제 내성균 모니터링에 관한 연구 / 한국미생물·생명공학회지 35(1):17~25
Rubin JE / 2014 / Extended-spectrum -lactamase, carbapenemase and AmpC producing Enterobacteriaceae in companion animals / Vet Microbiol 170:10~18
김명희 / 2010 / Molecular Characteristics of Extended Spectrum β-Lactamases in Escherichia coli and Klebsiella pneumoniae and the Prevalence of qnr in Extended Spectrum β-Lactamase Isolates in a Tertiary Care Hospital in Korea / Yonsei Medical Journal 51(5):768~774
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