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Purpose : Spin-echo (SE) technique is most commonly used pulse sequence for T1-weighted MR imaging. T1-weightedfluid-attenuated inversion recovery (T1FLAIR) is a relatively new pulse sequence and it provides higher tissue contrastbetween the gray matter (GM) and white matter (WM) of the brain than T1-weighted SE (T1SE) sequence. However,there has been controversy for the evaluation of enhancing brain tumors with T1FLAIR compared to T1SE. The purpose ofthis study was to compare T1FLAIR and T1SE sequences for the evaluation of enhancing intracranial tumors. Materials and Methods: Fifty-two patients with enhancing brain tumors were evaluated with contrast-enhanced (CE)T1SE and T1FLAIR imaging. Eight quantitative criteria were calculated: lesion-to-WM contrast ratio (CR) and contrast-tonoiseratio (CNR), lesion-to-GM CR and CNR, lesion-to-CSF CR and CNR, and WM-to-GM CR and CNR. For qualitativeevaluation, two radiologists assessed lesion conspicuity on CE T1SE and T1FLAIR sequences with three-scale: 1, T1SEsuperior; 2, sequence equal; T1FLAIR superior. Results: Seventy-nine tumors (31 primaries, 48 metastases) were assessed. For quantitative measurement, the T1FLAIRlesion-to-GM, lesion-to-CSF, WM-to-GM CR and CNR values were comparable and statistically superior to those of theT1SE images (p < 0.001 in all). However, lesion-to-WM CR and CNR were similar on both two sequences without statisticallysignificant difference (p = 0.661, 0.662, respectively). For qualitative evaluation, both radiologists assessed thatT1FLAIR images were superior to T1SE images for the evaluation of lesion conspicuity. Conclusion: For the evaluation of enhancing intracranial tumors, T1FLAIR sequence was superior or comparable to T1SEsequence.

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