Optimal Continuous Positive Airway Pressure Level in Korean Patients with Obstructive Sleep Apnea Syndrome

최지호; 김은중; 김강우; 최준; 권순영; 이흥만; 김태훈; 이상학; 신철; 이승훈

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자료유형: 학술저널

저자정보: 최지호 김은중 김강우 최준 권순영 이흥만 김태훈 이상학 신철 이승훈

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제3권 제4호

발행연도: 2010.1

수록면: 207 - 211 (5page)

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Objectives. The aim of this study was to investigate optimal continuous positive airway pressure (CPAP) level, to examine the factors affecting optimal CPAP level, and to develop a predictive equation for optimal CPAP level in Korean patients with obstructive sleep apnea syndrome (OSAS). Methods. A total of 202 patients with OSAS who underwent successful manual titration for CPAP treatment were included in this study. Correlations between the optimal CPAP level and baseline data including anthropometric and polysomnographic variables were analyzed. A predictive equation for optimal CPAP level was developed based on anthropometric and polysomonographic data. Results. The mean optimal CPAP level in 202 patients with OSAS was 7.8±2.3 cm H2O. The mean optimal CPAP level in the mild, moderate, and severe OSAS groups was 6.0±1.3, 7.4±1.9, and 9.1±2.1 cm H2O, respectively. The apneahypopnea index (AHI) (r=0.595, P<0.001), arousal index (r=0.542, P<0.001), minimal SaO2 (r=-0.502, P<0.001),body mass index (BMI) (r=0.494, P<0.001), neck circumference (r=0.265, P<0.001), and age (r=-0.164, P=0.019)were significantly correlated with optimal CPAP level. The best predictive equation according to stepwise multiple linear regression analysis was: Optimal CPAP level (cm H2O)=0.681+(0.205×BMI)+(0.040×AHI). Forty-two percent of the variance in the optimal CPAP level was explained by this equation (R2=0.42, P<0.001). Conclusion. A predictive equation for optimal CPAP level in Korean patients with OSAS was developed using AHI and BMI, which can be easily measured during the diagnostic process.

#Obstructive sleep apnea syndrome #Continuous positive airway pressure #Polysomnography #Body mass index

참고문헌 (22)

참고문헌 신청

Akahoshi T / 2009 / Predicting optimal continuous positive airway pressure in Japanese patients with obstructive sleep apnoea syndrome / Respirology 14 (2) : 245 ~ 250

Akashiba T / 2001 / Optimal continuous positive airway pressure in patients with obstructive sleep apnoea:role of craniofacial structure / Respir Med 95 (5) : 393 ~ 397

Ballester E / 1999 / Evidence of the effectiveness of continuous positive airway pressure in the treatment of sleep apnea/hypopnea syndrome / Am J Respir Crit Care Med 159 (

Choi JH / 2009 / Efficacy study of a vest-type device for positional therapy in position dependent snorers / Sleep Biol Rhythms 7 (3) : 181 ~ 187

Epstein LJ / 2009 / Clinical guideline for the evaluation,management and longterm care of obstructive sleep apnea in adults / J Clin Sleep Med 5 (3) : 263 ~ 276

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