지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 692 - 699 (8page)
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초록· 키워드
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Background and Objectives Eosinophilic otitis media (EOM) is characterized by the presence of a highly viscous effusion containing eosinophils. It mainly occurs in patients with bronchial asthma, nasal polyps and is resistant to conventional treatments for otitis media. In these patients, steroid is very effective in controlling the disease. However, the major complication is sensorineural hearing loss, especially at high frequencies, which may occur despite steroid therapy.
Subjects and Method Here we report 10 cases of EOM at Seoul National University Hospital.
Clinical courses and characteristics of the patients were analyzed. We compared the hearing deterioration and other clinical variables between EOM patients and age-matched non-EOM chronic otitis media patients.
Results All cases had viscous effusion and 9 cases were associated with asthma and nasal polyps. All patients had a decreased hearing in high frequency range compared to the age matched controls. The average bone conduction threshold difference at 2 kHz, 4 kHz was 22.4dB HL and 42.5 dB HL, respectively. Among the patients, one showed profound sensorineural hearing loss bilaterally after the onset of EOM and received cochlear implantation. The open set sentence score was 82% 6 months after cochlear implantation. Most of the cases were resistant to conventional treatments for otitis media, such as administration of antibiotic agents,ventilation tube insertion or mastoidectomy. However, cases that were given steroid treatment had improvement in ear symptoms.
Conclusion Since EOM patients show deterioration of hearing, it is important to properly diagnose EOM, start adequate treatment and explain to patients that the disease may last for a long period and progressive hearing loss may occur.
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참고문헌 (19)
참고문헌 신청
Holgate S / 2005 / The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation / J Allergy Clin Immunol 115 (3) : 459 ~ 465
Iino Y / 2001 / Eosinophils are activated in middle ear mucosa and middle ear effusion of patients with intractable otitis media associated with bronchial asthma / Clin Exp
Iino Y / 2005 / Eosinophil chemoattractants in the middle ear of patients with eosinophilic otitis media / Clin Exp Allergy 35 (10) : 1370 ~ 1376
Iino Y / 2008 / Bone conduction hearing level in patients with eosinophilic otitis media associated with bronchial asthma / Otol Neurotol 29 (7) : 949 ~ 952
Iino Y / 2008 / Eosinophilic otitis media: a new middle ear disease entity / Curr Allergy Asthma Rep 8 (6) : 525 ~ 530
Iino Y / 2001 / Eosinophils are activated in middle ear mucosa and middle ear effusion of patients with intractable otitis media associated with bronchial asthma / Clin Exp
Iino Y / 2005 / Eosinophil chemoattractants in the middle ear of patients with eosinophilic otitis media / Clin Exp Allergy 35 (10) : 1370 ~ 1376
Iino Y / 2008 / Bone conduction hearing level in patients with eosinophilic otitis media associated with bronchial asthma / Otol Neurotol 29 (7) : 949 ~ 952
Iino Y / 2008 / Eosinophilic otitis media: a new middle ear disease entity / Curr Allergy Asthma Rep 8 (6) : 525 ~ 530
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