최소 침습적 수술을 위한 술 중 부갑상선 호르몬 측정의 유용성

이자현; 문경래; 김현지; 정성민; 김한수

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자료유형: 학술저널

저자정보: 이자현 문경래 김현지 정성민 김한수

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제52권 제5호

발행연도: 2009.1

수록면: 426 - 430 (5page)

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Background and Objectives：Intraoperative parathyroid hormone (PTH) assay has been proposed as an effective tool in minimally invasive parathyroidectomy. We evaluated its usefulness during minimally invasive parathyroidectomy. Subjects and Method：Ten patients (female 6, male 4) of primary hyperparathyroidism (8 single diseases, 2 multiple diseases) were analyzed retrospectively. We used computed tomography (CT) and 99mTc-Sestamibi (MIBI) scan for localization of parathyroid lesions preoperatively, and frozen biopsy and PTH assay at 10 (T-10), 20 (T-20) minutes after excision intraoperatively. We also compared the diagnostic sensitivity of CT and MIBI scan and intraoperative PTH. Results：All patients were treated successfully and in single disease group, diagnostic sensitivity of CT, MIBI scan were 75% and 87.5%, and that of T-10 was 75% and T-20 was 100%. In multiple disease group, diagnostic sensitivity of CT, MIBI scan were 75%, 87.5%, and that of PTH was 80%. Conclusion：Intraoperative PTH assay improves cure rate in minimally invasive parathyroidectomy. It allowed intraoperative recognition of missed parathyroid lesions by preoperative imaging study.

#부갑상선·술 중 부갑상선 호르몬 #Parathyroid·Intraoperative parathyroid hormone

참고문헌 (20)

참고문헌 신청

Carneiro DM / 2000 / Late parathyroid function after successful parathyroidectomy guided by intraoperative hormone assay (QPTH) compared with the standard bilateral neck exp

Carneiro DM / 2003 / Comparison of intraoperative iPTH assay (QPTH) criteria in guiding parathyroidectomy: Which criterion is the most accurate? / Surgery 134 (6) : 973 ~ 97

Chapuis Y / 1996 / Values of ultrasonography, sestamibi scintigraphy, and intraoperative measurement of 1-84 PTH for unilateral neck exploration of primary hyperparathyroidi

Chen H / 1996 / Parathyroidectomy in Maryland: Effects of an endocrine center / Surgery 120 (6) : 948 ~ 952

Chen H / 2005 / Intraoperative parathyroid hormone testing improves cure rates in patients undergoing minimally invasive parathyroidectomy / Surgery 138 (4) : 583 ~ 587

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