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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제8권 제4호
- 발행연도
- 2015.1
- 수록면
- 416 - 421 (6page)
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초록· 키워드
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Objectives. We describe patterns of tumor regression based on follow-up duration after radiotherapy (RT) or chemo-RT in patients with head and neck squamous cell carcinoma. Methods. Thirty-one patients with head and neck squamous cell carcinoma were included in this study and received definitive RT or chemo-RT. The pattern of primary tumor regression after treatment was evaluated every 1 to 2 months. Predictive factors for the length of time to full regression were also analyzed. Results. Among all patients, 27 patients showed regression of the primary tumor, 24 patients showed >50% regression, and 15 patients showed total regression. The primary tumor gradually regressed during the course of follow-up. The median time to full regression was 5.2 months (range, 1.3 to 17.9 months). In the 24 patients who showed >50% regression, the rate of >50% regression increased over time as follows: 25.0% at 1 month, 62.5% at 2 months, 75.0% at 3 months, 91.7% at 4 months, and 95.8% at 5 months. Higher total RT dose and shorter RT duration were associated with longer time to full regression. Conclusion. A substantial number of patients showed continuous regression of the primary tumor for more than 2 months after treatment. The timing for evaluation of tumor regression must be greater than 2 months from the completion of RT or chemo-RT in patients with head and neck squamous cell carcinoma.
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참고문헌 (15)
참고문헌 신청
Cooney TR / 1999 / Is routine follow-up useful after combined-modality therapy for advanced head and neck cancer? / Arch Otolaryngol Head Neck Surg 125 (4) : 379 ~ 382
Dias FL / 2013 / Assessment of treatment response after chemoradiation of head and neck cancer / Curr Oncol Rep 15 (2) : 119 ~ 127
Hermans R / 2000 / Mendenhall WM. Laryngeal or hypopharyngeal squamous cell carcinoma: can follow-up CT after definitive radiation therapy be used to detect local failure ea
Joshi A / 2010 / Current trends in the follow-up of head and neck cancer patients in the UK / Clin Oncol (R Coll Radiol) 22 (2) : 114 ~ 118
Kothari P / 2011 / The follow-up of patients with head and neck cancer: an analysis of 1,039 patients / Eur Arch Otorhinolaryngol 268 (8) : 1191 ~ 1200
Dias FL / 2013 / Assessment of treatment response after chemoradiation of head and neck cancer / Curr Oncol Rep 15 (2) : 119 ~ 127
Hermans R / 2000 / Mendenhall WM. Laryngeal or hypopharyngeal squamous cell carcinoma: can follow-up CT after definitive radiation therapy be used to detect local failure ea
Joshi A / 2010 / Current trends in the follow-up of head and neck cancer patients in the UK / Clin Oncol (R Coll Radiol) 22 (2) : 114 ~ 118
Kothari P / 2011 / The follow-up of patients with head and neck cancer: an analysis of 1,039 patients / Eur Arch Otorhinolaryngol 268 (8) : 1191 ~ 1200
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