A Relationship between the Obstructive Sleep Apnea Syndrome and the Erythrocyte Sedimentation Rate

민진영; 김효열; 동헌종; 정승규; 장전엽; 이원용; 정수찬

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자료유형: 학술저널

저자정보: 민진영 김효열 동헌종 정승규 장전엽 이원용 정수찬

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제2권 제3호

발행연도: 2009.1

수록면: 126 - 130 (5page)

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Objectives. The erythrocyte sedimentation rate (ESR) is a marker for inflammation, and it has been identified as a risk factor for atherothrombotic cardiovascular disease. The aim of this study was to determine the relationship between the plasma ESR level and nocturnal oxygen desaturation or other polysomnographic variables and to examine the role of obesity in patients with obstructive sleep apnea syndrome (OSAS). Methods. This retrospective study included 72 patients with a diagnosis of OSAS who underwent overnight polysomnography and routine blood tests between July and December of 2005. We compared the plasma ESR level with the sum of all the polysomnographic variables and divided the patient group into obese and non-obese patients. Results. The mean ESR level was 8.45 mm/hr. There was a significant difference in the ESR level between genders (P<0.001). A significant correlation was found between the percentage of time spent at a SpO2 below 90% and the ESR level in the obese group (BMI ≥25, N=43, P=0.012). In addition, the ESR levels had a positive correlation with age in the obese group (P=0.002). However, there was no significant correlation with the percentage of time spent at a SpO2 below 90% in the whole group of patients and in the non-obese group (BMI <25, N=29). The ESR level showed no correlation with the other polysomnographic variables. Conclusion. The duration of deoxygenation in obese patients with OSAS may be associated with the ESR level which is an independent predictor of cardiovascular disease.

#Blood sedimentation #Obstructive sleep apnea #Oximetry #Polysomnography

참고문헌 (22)

참고문헌 신청

Andresdottir MB / 2003 / Erythrocyte sedimentation rate, an independent predictor of coronary heart disease in men and women: the Reykjavik Study / Am J Epidemiol 158 (9) :

Carlson LA / 1979 / Risk factors for myocardial infarction in the Stockholm prospective study: a 14-year follow-up focussing on the role of plasma triglycerides and choleste

Dziewas R / 2005 / Increased prevalence of sleep apnea in patients with recurring ischemic stroke compared with first stroke victims / J Neurol 252 (11) : 1394 ~ 1398

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민진영

소속기관 Department of Otorhinolaryngology-Head and Neck Surgery Kyung Hee University Medical Center