구강 Schirmer 검사를 이용한 타액선 기능의 진단

주형로; 김창훈; 이종선; 박수경; 고은석; 노영수

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자료유형: 학술저널

저자정보: 주형로 김창훈 이종선 박수경 고은석 노영수

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제51권 제2호

발행연도: 2008.1

수록면: 153 - 156 (4page)

이용수

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연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

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The accurate measure of salivary flow rate requires a variety of clinical and experimental protocols. Several methods have traditionally been used to collect and measure the whole mouth saliva. The objective of this study was to verify usefulness of a newly developed oral Schirmer test for detecting salivary gland hypofunction. Subjects and Method： The control group consisted of 85 healthy patients, while another group consisted of 30 patients with salivary grand resection or post-head and neck irradiation and a third group of 30 patients who suffered from subjective xerostomia caused by other pathologies. Oral Schirmer test was carried out in all subjects. The main outcome was the wetted length after 5 minutes. Results：The mean saliva flow was 59.3±16.99 mm/5 min in the control group, 47.0±13.50 mm/5 min in the 2nd group and 39.9±11.65 mm/ 5 min in the third group. The differences between the control group and the other two groups were statistically different (p<0.001). A cut-off value 40 mm/5 min showed sensitivity of 83.7% and specificity of 62.5%. Conclusion：The oral Schirmer test is valid and reliable for identifying subjects with xerostomia. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:153-6)

#Salivary gland·Xerostomia.

참고문헌 (19)

참고문헌 신청

Aframian DJ / 2004 / Characterization of murine autologous salivary gland cells: A model for use with an artificial salivary gland / Tissue Eng 10 (5) : 914 ~ 920

Atkinson JC / 1994 / Salivary gland dysfunction: Causes, symptoms, treatment / J Am Dent Assoc 125 (4) : 409 ~ 416

Cassolato SF / 2003 / Xerostomia: Clinical aspects and treatment / Gerodontology 20 (2) : 64 ~ 77

Davis CC / 1986 / The use of the Schirmer tear test in evaluating mouth dryness / Dent Hyg 60 (3) : 116 ~ 119

Dawes C / 1987 / Physiologic factors affecting salivary flow rate, oral sugar clearance, and the sensation of dry mouth in man / J Dent Res 66 : 648 ~ 653

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