비중격 만곡 환자 연골에서 외상 유무 및 시기에 따른 조직학적 변화

김종엽; 최종철; 김범경; 박병건; 인승민

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자료유형: 학술저널

저자정보: 김종엽 최종철 김범경 박병건 인승민

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제49권 제6호

발행연도: 2006.1

수록면: 629 - 635 (7page)

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Background and Objectives：The histologic difference of the traumatic nasal septal cartilage from that of non-traumatic has not been extensively studied. The aim of this study was to identify histologic difference in the nasal septal cartilage between traumatic and non-traumatic nasal septal deviation and to find its implication for surgical intervention. Subjects and Method： Nasal septal cartilage was obtained from 23 patients who had undergone septoplasty or septorhinoplasty for the nasal septal deviation. The septal cartilage without trauma (7 patients, Group I) and with the history of the trauma at the age under 10-15 years old (8 patients, Group II), and over 25 years old (8 patients, Group III) between May 2003 to February 2005 were included in this study. An approximately 11 cm sized piece of the septal cartilage was harvested from the site deviated the most. The histologic difference of the septal cartilage by hematoxylineosin staining under a light microscope was performed. Results：The chondrocyte densities were significantly higher in the convex side than in the concave side of the septal cartilage in Group I, II, III. Especially, the increased chondrocyte ratio (convex/concave) were more evident in the septal cartilage traumatized at the age of 10 to 15 years, and the cartilage plate was thicker than the other groups (p<0.001). Also, dystrophic changes of the chondrocytes as representing the chondrocyte differentiation and chondroblast ratio (convex/concave) were significantly higher in the group II than in the other groups (p<0.005). Conclusion：This study demonstrated that age dependent changes in septal cartilage with nasal trauma showed distinctive histologic characteristics. We suggest that these observations will help determine surgicaltreatment modality for cases of nasal septal deviations with and without trauma. (Korean J Otolaryngol 2006;49:629-35)

#비중격 만곡·비중격 연골·외상. #Septal deviation·Septal cartilage·Trauma.

참고문헌 (15)

참고문헌 신청

/ 1970 / Septorhinoplasty in children 3 : 345 ~ 64

/ 1983 / The effects of nasal trauma during childhoodupon growth of the nose and midface 10 : 38 ~ 41

/ 1984 / Growth of the humanseptal cartilage:Cell density and colony formation of septalchondrocytes 94 : 1226 ~ 9

/ 1984 / Postnatal growth of the human septalcartilage.Preliminary report 97 : 131 ~ 6

/ 1987 / The role of maxillar morphology in the development ofpathological septal deformities 25 : 199 ~ 205

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